_______________________________________________________________________________________________________________________________ 290 http://www.mjms.mk/ http://www.id-press.eu/mjms/ ID Design 2012/DOOEL Skopje, Republic of Macedonia Open Access Macedonian Journal of Medical Sciences. 2016 Jun 15; 4(2):290-292. http://dx.doi.org/10.3889/oamjms.2016.048 eISSN: 1857-9655 Stomatology Oncocytoma of the Deep Lobe of the Parotid Gland Vladimir Popovski 1 , Alberto Benedetti 1 , Danica Popovik Monevska 1 , Aleksandar Grcev 1 , Predrag Serafimovski 1 , Ruse Pecanovski 1 , Aleksandar Stamatoski 2* 1 University Clinic for Maxillofacial Surgery, Faculty of Dental Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia; 2 Faculty of Dental Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia Citation: Popovski V, Benedetti A, Popovik Monevska D, Grcev A, Serafimovski P, Pecanovski R, Stamatoski A. Oncocytoma of the Deep Lobe of the Parotid Gland. Open Access Maced J Med Sci. 2016 Jun 15; 4(2):290-292. http://dx.doi.org/10.3889/oamjms.2016.048 Key words: Salivary gland tumors; Parotid gland neoplasm; Oncocytoma; MRI; Parotidectomy. *Correspondence: Dr. Aleksandar Stamatoski. Faculty of Dental Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia. E-mail: alexandar.stamatoski5999@gmail.com Received: 11-Mar-2016; Revised: 21-Mar-2016; Accepted: 22-Mar-2016; Online first: 23-Mar-2016 Copyright: © 2016 Vladimir Popovski, Alberto Benedetti, Danica Popovik Monevska, Aleksandar Grcev, Predrag Serafimovski, Ruse Pecanovski, Aleksandar Stamatoski. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Competing Interests: The authors have declared that no competing interests exist. Abstract BACKGROUND: Oncocytoma or oxyphilic adenoma is uncommon salivary gland tumour, occurs predominantly in the in patients older than 60 years of age. Clinically oncocytoma resemble other salivary tumours while histology is typically consisting of oncocytes with many hyperplastic mitochondria. It usually occurs in the parotid gland. Because the features of oncocytoma are similar to those of other benign and low-grade malignant salivary tumours, clinical diagnosis is often challenging. CASE PRESENTATION: This report presents the pathologic and imaging findings of an oncocytoma arising in the deep lobe of the right parotid gland in a 74-year-old male. Oncocytoma was diagnosed on the basis of histological, magnetic resonance imaging (MRI), scintigraphic findings and fine needle aspiration cytology (FNAC). CONCLUSION: This case was unique because in the literature there are few articles about the rare presentation and deep lobe location of this type of parotid oncocytoma. Introduction Oncocytoma or oxyphilic adenoma is a rare benign salivary gland tumor, which mostly occurs in the parotid glands, few affect the submandibular and rarely affect the minor salivary glands [1-4]. Oncocytoma of parotid gland occurs most commonly in patients older than 60 years of age. Oncocytomas are composed of mitochondria-rich epithelial cells called oncocytes [2, 5]. The oncocytes may be present of conditions ranging from hyperplasia to malignant lesions, but the presence of true oncocytes within the entire lesion is a hallmark of oncocytomas [6, 9]. Histologically there are three distinct types: oncocytosis, oncocytoma (the most common form) and oncocytic carcinoma [6]. The clinical presentation of oncocytomas is usually identical to other benign salivary tumors. The image modalities of choice to identify the well-defined homogeneous mass are CT Scan MRI, ultrasonography, radionuclide salivary scintigraphy and positron emission tomography CT scans [11, 12]. Complete surgical removal with superficial or total parotidectomy is the treatment of choice, whereas radiation therapy is not indicated because oncocytes are radioresistant [8]. Recurrence is unusual and probably results from incomplete initial resection. Malignant transformation is occasionally reported [13]. Long-term follow-up using imaging refinements is recommended to evaluate the patient's progress. Here we are presenting the case of a 74- years-old male patient with right oncocytoma of the