Background: Guidelines of treatment with antipsychotic medication have changed in the last 10 years, following the marketing of atypical antipsychotic medication (1994), being at the beginning the more fre- cuently use of typical antipsycotics and classic Depot in opposite to oral and depot atypical antipsychotics at the present. Aims: To describe the real situation about the use of antipsy- chotics in patients with Schizophrenia following hospitalization into the different Acute Hospitalary Units and differences in their first and subsequent admission. Methods: A survey was conducted by different hospitals in our geography from the discharge reports occurred in 2006 on schizo- phrenic patients. Results: 2424 discharge reports were analized from 6 Acute Hos- pitalary Units. They were obtained 601 schizophrenic patients (24.79%) that required rehospitalization in 15.2% (N¼76). The aver- age stay was two to three weeks. Most patients were diagnosed of Paranoid Schizophrenia (74;75%). The more frecuently used was oral and/or IM atypical antipsychotic medication at 43%, opposite to 22.30 of the atypicals antipsycotics. The predominant antipsychotic association used was a typical oral antipsychotic with atypical depot (26.47%), followed by the associa- tion of typical antipsychotic with oral atypical antipsychotic in 10.625. In readmissions the differences between both groups faded (atypical antipsychotics, 33.57% and combinations with depot, 30.26%) Conclusion: There has been an evolution in the pattern of use of antipsychotic medication in the last 10 years. From predominant use of typical antipsychotics we have switched to atypical antipsychotics in monotherapy in first place (50% of patients), followed by the asso- ciation of atypical antipsychotic plus depot. P0222 Delusional beliefs among subjects with schizophrenia, their healthy relatives, and normal subjects V. Sharifi 1,2 , N. Yaghoubpour Yekani 1,2 , M. Mohammadi 1,2 , H. Amini 1,2 . 1 Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran 2 Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, Iran Background and Aims: To investigate delusional beliefs and their dimensions (distress, preoccupation, conviction) across three groups, including patients with schizophrenia, their healthy family members, and normal subjects. Methods: Subjects were 25 patients with schizophrenia, 35 of their healthy first degree relatives, and 35 normal subjects. Frequency of delusional beliefs and their dimensions were assessed using Peters et al. Delusions Inventory (PDI-40). General Health Questionnaire (GHQ-28) was used to examine general mental health. Results: Frequency of delusional beliefs was higher in the pa- tient group, compared with family group and normal subjects. Scores of all three dimensions of beliefs among the patients were significantly higher than the normal subjects but not more than their family members. In addition, conviction in the beliefs was signifi- cantly higher in the family members as compared to normal subjects. Conclusions: The existence of the delusional beliefs among the healthy family members of patients with schizophrenia and the higher conviction in these beliefs as compared to normal subjects is in keeping with the continuum notion of psychosis. Further investiga- tions are needed to support the notion. P0223 Duration of untreated psychosis and pathways to care in patients with first episode psychosis in Iran V. Sharifi 1,2 , T. Kermani-Ranjabar 1,2 , H. Amini 1,2 , J. Alaghband- rad 1,2 , N. Salesian 1 , A. Seddigh 1 . 1 Department of Psychiatry, Roozbeh Hospital, Tehran, Iran 2 Psychiatry and Psychology Research Center, Roozbeh Hospital, Tehran, Iran Background and Aims: This is the first study of duration of un- treated psychosis and pathways to care among patients with first ep- isode psychosis in Iran. Methods: Subjects were patients with a first episode of a nonor- ganic psychotic illness that were admitted to a university affiliated psychiatric hospital in Iran. Patients were assessed for duration of un- treated psychosis (DUP, defined as the duration between the appear- ance of first symptoms of psychosis and the time when first adequate treatment is received), pathways to care (including any previous help- ing contacts and referrals to the hospital), and mode of illness onset. Results: Ninety-one patients were enrolled. Median DUP was 11 weeks, with the mean of 52.3 weeks (range: one day to 17 years). Fol- lowing the onset of psychosis, most patients were first seen by a psy- chiatrist (n¼23, 25.3%), a traditional healer (n¼21, 23.1%) or a general practitioner (n¼16, 17.6%). Most of the referrals to the psy- chiatric hospital was by the family (n¼30, 33.1%), and health profes- sionals (n¼ 29, 31.9%). Acute illness onset and rural place of residence were associated with shorter DUP in multivariate analysis. Conclusions: DUP in this developing country setting was compa- rable to several others in western countries. This may be due to the preponderance of acute psychoses in this sample, and different help seeking behavior or health care system. Of special notice, family plays a significant role in the journey toward care. P0224 Psychotic-like experiences in general population: Prevalence and cor- relates in an urban dwelling population in Iran V. Sharifi 1,2 , L. Faghih Nasiri 3 , Z. Sadeghianmehr 3 , S. Mirkia 3 , Z. Hatmi 4 , S. Darbooy 3 , M. Effatpanah 3 , M. Mirsharifa 5 . 1 Department of Psychiatry, Tehran University of Medical Sciences, Tehran, Iran 2 Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, Iran 3 Undersecretary of Health, Tehran University of Medical Sciences, Tehran, Iran 4 Department of Community Medicine, Tehran University of Medical Sciences, Tehran, Iran 5 Consultation Center, Ministry of Oil, Tehran, Iran Background and Aims: To assess psychotic-like experiences and their correlates in a large sample of urban dwelling general popula- tion in Tehran, the capital city of Iran. Methods: A random sample of 2158 subjects aged 18 -65 residing in a densely populated area in southern Tehran was surveyed. Psy- chotic-like experiences were assessed with the Symptom Checkliste90eRevised (SCL90-R) symptom dimensions ‘‘paranoid ideation’’ and ‘‘psychoticism’’. Paykel’s Interview for Recent Life Events was used to examine recent and past stressful life events. Results: Using ‘‘moderately experienced’’ cut-off level, the prev- alence of psychoticism symptoms ranged from 9.4% (Having S146 Abstracts for Poster Session I / European Psychiatry 23 (2008) S81eS191