Open Peer Review F1000 Faculty Reviews are commissioned from members of the prestigious F1000 . In order to make these reviews as Faculty comprehensive and accessible as possible, peer review takes place before publication; the referees are listed below, but their reports are not formally published. Discuss this article (0) Comments REVIEW Pancreatic neuroendocrine tumors: the basics, the gray zone, and the target [version 1; referees: 3 approved] Dionysia Kelgiorgi , Christos Dervenis 2 Department of Surgery, Euroclinic Athens, Athens, Greece Department of Surgical Oncology and HPB Surgery, Metropolitan Hospital, Athens, Greece Abstract Pancreatic neuroendocrine tumors (PanNETs) manifest with a range of symptoms and pose a therapeutic challenge. A team approach, in which many specialists come together, is necessary in the quest for the best patient-tailored treatment. Disciplines such as oncology, surgery, basic science, endocrinology, radiology, and nuclear medicine need to work side by side, equally contributing to patient care and to advancing our better understanding of this fascinating disease. 1 2 1 2 Referee Status: Invited Referees version 1 published 10 May 2017 1 2 3 , The University of Texas Arvind Dasari MD Anderson Cancer Center USA 1 , Johns Hopkins Hospital Ralph Hruban USA 2 , University of Ferrara Italy Maria Zatelli 3 10 May 2017, (F1000 Faculty Rev):663 (doi: First published: 6 ) 10.12688/f1000research.10188.1 10 May 2017, (F1000 Faculty Rev):663 (doi: Latest published: 6 ) 10.12688/f1000research.10188.1 v1 Page 1 of 10 F1000Research 2017, 6(F1000 Faculty Rev):663 Last updated: 12 MAY 2017