27 Med Arh. 2012 Jun; 66(3, suppl 1): 27-29 • ORIGINAL PAPER Spermiogram Part of Population with the Manifest Orchtis During an Ongoing Epidemic of Mumps DOI: 10.5455/medarh.2012.66.s27-s29 Med Arh. 2012 Jun; 66(3, suppl 1): 27-29 Received: April 10th 2012 Accepted: May 25th 2012 CONFLICT OF INTEREST: NONE DECLARED ORIGINAL PAPER Spermiogram Part of Population with the Manifest Orchtis During an Ongoing Epidemic of Mumps Belma Gazibera, Refet Gojak, Alija Drnda, Akif Osmic, Nermin Mostarac, Ilhama Jusuf-Huric, Planinka Muratovic Clinic for the Infectious Diseases, Clinical center of University of Sarajevo, Sarajevo, Bosnia and Herzegovina I ntroduction: Incidence mumps infection has declined since the introduction of the inevitable MRP vaccination during the stage of childhood.  In Bosnia and Herzegovina (BIH), from a period of February 2011 until today, there is an evident inclination of the recorded cases of the mumps infection. Orchitis usually occurs in between 3 to 10 days after the parotitis and is found with the post-puberty popula- tion. Aim: Te aim of the study is to confrm the changes that occur during an early stage of the spermiogram and hormonal status, and after treated mumps orchitis, the patients treated in the Clinic for the Infectious Diseases. Patients and Meth- ods: Retrospectively, the analysis of 54 historical diseases was undertaken. During the research stage, the patients after being discharged have made an inquiry to our clinical consultancy units with fnal results of the spermiogram and hormone-FSH, LH and testosteron. Te data analysis was processed with the SPSS program for Windows. Results: the average length of the hospitalization period was in between 8 (medium) days, and average age M (mean) = 21, 9±5,4 years. Te speriogram of the treated patients was undertaken one month after the acute phase of the disease and has shown the following results: azoospermia with 14 patients (25,9%), oligospermia with 30 patients (55,6%) and normospermia with 10 patients (18,5%). During the hormonal status with 11 patients (20,4%), the results have shown the inclination of the value in FSH hormons, with 11 patients (20,4%), have shown the lesser value of the testosterons. Conclusion: Te current study suggests that post-orhitis atrofa is expected within a period of 2-3 months after the infection, and thus, the moni- toring on the patients’ treatment would continue. Te male infertility as a result of mumps ocrhitis is controversial and continues to be the thematic issue as well as the efect of orchitis on testicular endocrine function. Key words: epidemic, mumps infection, spermiogram, orchitis. Corresponding author: Belma Gazibera, MD. Clinic for Infectious Diseases. Clinical center of Sarajevo University. 71000 Sarajevo. Bolnicka 25. Tel.+387 33 297 253.E-mail: gazibera.belma@gmail.com. 1. INTRODUCTION The CDC empirically defines mumps as the acute onset of unilateral or bilateral tender, self-limited swelling of the parotid or other salivary glands longer then 2 days without another ap- parent cause (1). Te mumps virus be- longs to the family Paramyxoviridae, spread by airborne droplets and the incubation period is 14-21 days, with an infectious period from two days be- fore onset of parotitis to 9 days after- wards (2, 3, 4). Since the introduction of the measles-mumps-rubella (MMR) vaccine in 1968 there has been a 99% reduction in the incidence of the vi- rus in the USA (5). Infection results in lifelong immunity. After adolescence, mumps can afect the gonads of both man abd women (6). Mumps orchitis is a major complications of a general in- fection vith the mumps virus. In 20 to 25% of man it can involve the testicles (orchitis), unilateral or bilateral. Or- chitis typically appears 3-10 days after the onset of parotitis, bat it may occur in the apsence of parotid involvement. In clinical suspicion (painful swelling of the testicle), history of parotitis and evidence of IgM antibodies in serum provide the diagnosis (5, 7). Infertility in male patients resulting from mumps orchitis is a contraversal, as there is conficting evidence on the endocrine function of the testes (5). Te therapy of mumps orchitis is not standardised. Te use of systemic α-2b interferon to prevent testicular atrophy has been sug- gested in several studies. Tis therapy has demonstrated a superior outcome in terms of men sperm count and per- centage normal morphology (8). On the other hand, testicular biopsy after in- terferon therapy has revealed testicu-