Terena Amerindian group autosomal STR data: comparison studies with other Brazilian populations F. S. N. Manta • D. A. Silva • P. Sa ´nchez-Diz • J. I. A. Aguiar • P. H. Cabello • E. F. Carvalho Received: 29 April 2011 / Accepted: 13 September 2011 Ó Springer Science+Business Media B.V. 2011 Abstract Allele frequencies for the high polymorphic short tandem repeats (STR) loci PentaE, PentaD, D18S51, D21S11, TH01, D3S1358, FGA, D16S539, D7820, D13S317, vWA and D81179 were analysed in an native Amerindian population from Mato Grosso do Sul state named Terena. Deviations from Hardy–Weinberg expecta- tions were evaluated and the results showed no differences from equilibrium in all loci. The combined power of dis- crimination and the combined power of exclusion for the 12 tested STR loci were 0.99999999 and 0.999999 respectively. The Terena population data were compared to other from 11 Brazilian populations (Amazo ˆnia, Pernambuco, Mato Grosso do Sul, Sa ˜o Paulo, Rio Grande do Sul, Alagoas, Sergipe, Rio Grande do Norte, Santa Catarina, Rondo ˆnia and Rio de Janeiro) representing the major Brazilian geographic regions. The F ST comparative analysis showed no significant differences between all those populations except when comparing Terena with the remained ones. Keywords Population genetics  STR loci  Terena  Brazil Introduction In the recent past, DNA microsatellites loci have been used for forensic purposes. Population genetic studies focusing on parameters such as frequency of polymorphic alleles, adherence to the expectations of Hardy–Weinberg equi- librium and loci independence are used for estimating DNA profile frequencies. Examination of genetic differ- entiation especially among ethnically defined and isolated populations with smaller effective sizes is also a quite relevant approach that has been used to evaluate the fitness of worldwide population database to forensic needs in order to attend the National Research Council recommen- dation for computing statistical significance of a DNA match, for instance [1]. The Brazilian population composed primarily of Euro- pean, African and Amerindian descendents is one of the most heterogeneous in the world. The admixture process occurred in different ways and proportions in the different geographic regions of the country [2]. In the last 10 years, several regional short tandem repeats (STR) databases have been constructed to population genetics and forensic pur- poses [3, 4]. However, population genetic studies carried out by analysis of STR markers within the indigenous Brazil populations are still scarce. The aim of this study was to carry out genetic studies enclosing the Terena Amerindian group living in Mato Electronic supplementary material The online version of this article (doi:10.1007/s11033-011-1234-z) contains supplementary material, which is available to authorized users. F. S. N. Manta (&)  D. A. Silva  E. F. Carvalho DNA Diagnostic Laboratory (LDD), Rio de Janeiro State University, Rua Sa ˜o Francisco Xavier, 524. Maracana ˜, Rio de Janeiro 20510-013, Brazil e-mail: femanta@yahoo.com.br P. Sa ´nchez-Diz Institute of Forensic Sciences Luis Concheiro, Genomics Medicine Group, University of Santiago de Campostela, Santiago de Campostela, Spain J. I. A. Aguiar Department of Internal Medicine, Faculty of Medical Science, Federal University of Mato Grosso do Sul, Campo Grande, Brazil P. H. Cabello Human Genetics Laboratory, Oswaldo Cruz Institute, Rio de Janeiro, Brazil 123 Mol Biol Rep DOI 10.1007/s11033-011-1234-z