*Correspondence: mitesh_dwivedi@yahoo.com; +91-2625-254122. (Received: December 25, 2019; accepted: February 06, 2020) Citaton: Nikita Patel, Mitesh Dwivedi, Shahnawaz Jadeja and Rasheedunnisa Begum, Antbacterial Actvity of Marine Bacterial Pigments Obtained from Arabian Sea Water Samples, J. Pure Appl. Microbiol., 2020; 14(1):517-526. htps://doi.org/10.22207/ JPAM.14.1.54 © The Author(s) 2020. Open Access. This artcle is distributed under the terms of the Creatve Commons Atributon 4.0 Internatonal License which permits unrestricted use, sharing, distributon, and reproducton in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creatve Commons license, and indicate if changes were made. Patel et al., J. Pure Appl. Microbiol., 14(1), 517-526 | March 2020 Artcle 5877 | htps://doi.org/10.22207/JPAM.14.1.54 Print ISSN: 0973-7510; E-ISSN: 2581-690X RESEARCH ARTICLE OPEN ACCESS www.microbiologyjournal.org 517 Journal of Pure and Applied Microbiology Antbacterial Actvity of Marine Bacterial Pigments Obtained from Arabian Sea Water Samples Nikita Patel 1 , Mitesh Dwivedi 1 *, Shahnawaz Jadeja 2  and Rasheedunnisa Begum 2  1 C.G. Bhakta Insttute of Biotechnology, Faculty of Science, Uka Tarsadia University, Maliba Campus, Bardoli, Gujarat - 394 350, India. 2 Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat - 390 002, India. Abstract The Arabian Sea environment harbors numerous microorganisms that have developed unique metabolic abilites to ensure their survival in hostle habitats. The bacterial pigments are considered to be important metabolic product which is useful for bacteria and may exert specifc biological propertes including antbacterial actvity. Moreover, there is an imperatve need for exploring new antbacterial agents since; there are drug resistance issues with the existng antbiotcs. Therefore, the present study was aimed to assess antbacterial actvity of pigments extracted from marine bacteria of Arabian Sea water samples and to characterize the potent antbacterial pigment producing isolate. The water samples were obtained from Tithal (Valsad), Diu, Daman and Dandi beaches of India. Total 9 distnct pigmented bacteria were isolated. The pigments extracted from bacterial isolates were assessed for the antbacterial, antoxidant and antcancer actvites. Four pigment producing isolates (NP5, NP6, NP8 & NP9) among the nine isolates showed good antbacterial actvity against the diferent bacterial cultures. Among these four isolates, NP9 showed maximum antbacterial actvity against all the test cultures. The pigment obtained from NP5 isolate exhibited higher antoxidant property as compared to NP6, NP8 and NP9. However, none of the pigments obtained from NP5, NP6 and NP9 exhibited ant-cancerous actvity on MCF-7 cell line. The molecular identfcaton by16srDNA sequencing revealed that NP9 belongs to Candidatus chryseobacterium massiliae (MK213063). Chryseobacterium has been known to produce yellow pigment; however, for the frst tme, the study suggests that Candidatus chryseobacterium massiliae strain produces red pigment with potent antbacterial actvity. However, its antbacterial actvity must be tested with more number of pathogens and study in disease animal model is needed to confrm the results of the study. Keywords: Arabian sea, Bacteria pigments, antbacterial, antoxidant and antcancer actvites