INTERNATIONAL ARCHIVES OF MEDICINE SECTION: TOXICOLOGY & THERAPEUTICS ISSN: 1755-7682 International Medical Society http://imedicalsociety.org 1 2017 Vol. 10 No. 58 doi: 10.3823/2328 © Under License of Creative Commons Attribution 3.0 License This article is available at: www.intarchmed.com and www.medbrary.com Abstract Introduction: The Synadenium grantii Hook f. species is a medici- nal plant of the Euphorbiaceae family and is popularly known in the Midwest regions of Brazil as leitosinha or janaúba. All the parts of Synadenium grantii Hook f. as stem, latex, leaves and fowers are used for the treatments of various disease, but no elemental composition has been done. Objective: The aim of present work was to measure the macroe- lements (K, Mg, Mo and P) and microelements (Cr, Cu, Fe, Mn, Mo, Zn, Si, Ni, Co, Cd and Al) in the leaves of medicinal plant Synadenium grantii Hook f. used in the treatment of diseases by rural and urban communities of the Campo Grande, State of Mato Grosso do Sul, Brazil. Method: The chemical digestions of samples were prepared utilizing HNO 3 and H 2 O 2 and microwave digestion system Speedwave Berghof, Germany. After digestion, the concentrations of the elements in leaves were determined by technique of Inductively Coupled Plasma – Optical Emission Spectrometer (ICP-OES) with a Dual Plasma (Thermo Scien- tifc – iCAP 6000 Series) Results: Results demonstrated that the Synadenium grantii Hook f. leaves are source of K but aren't the best source of Na and P. Its lea- ves are rich in elements such as Mg, Cr, Cu, Fe, Mn, Mo and Zn. The leaves of Synadenium grantii Hook f. showed a high content of Mg values tolerable upper intake level. However, Fe, Na, P, Mn, Mo and Identification of Macroelements and Microelements in the Leaves of the Synadenium Grantii Hook Used as Medicinal Plant in the Brazil ORIGINAL Igor Domingos de Souza 1 , Ana Lucia Alves de Arruda 2 , Anderson Fernandes da Silva 1 , Rafaela Henriques Rosa 2 , Marcos Antonio Ferreira Júnior 3 , Valter Aragão do Nascimento 4 , Rita de Cássia Avellaneda Guimarães 5 1 School of Medicine, Postgraduation Program in Health and Development in the Middle West Region, Federal University of Mato Grosso do Sul, Brazil, Campo Grande, MS, Brazil. 2 Faculdade Unigran Capital, Abrao Júlio Rahe, 325, Campo Grande, MS, Brazil. 3 Federal University of Rio Grande do Norte, Natal/RN, Brazil. Av. Senador Salgado Filho, S/N, Campus Universitário, Lagoa Nova, Natal/RN. 4 Scholl of Medicine, Postgraduation Program in Health and Development in the Middle West Region, Federal University of Mato Grosso do Sul, Brazil, Campo Grande, MS, Brazil. 5 Postgraduation Program in Health and Development in the Middle West Region, Federal University of Mato Grosso do Sul, Brazil, , Campo Grande, MS, Brazil. Contact information: Valter Aragão do Nascimento.  aragao60@hotmail.com