Title: Auranofin inhibits virulence in Pseudomonas aeruginosa 1 2 Authors: Leon Zhen Wei Tan 1,2,6 , Ziyan Hong 2,6 , Joey Kuok Hoong Yam 2,3 , May Margarette 3 Santillan Salido 2 , Bau Yi Woo 1 , Sam Fong Yau Li 1 , Liang Yang 2,4 , Michael Givskov 2,5* , Shu- 4 Sin Chng 1,2* 5 6 Affiliations: 7 1 Department of Chemistry, National University of Singapore, Singapore 117543. 8 2 Singapore Center for Environmental Life Sciences Engineering (SCELSE), Singapore. 9 3 Interdisciplinary Graduate School, Nanyang Technological University, Singapore 637551, 10 Singapore. 11 4 School of Biological Sciences, Nanyang Technological University, Singapore 639798, 12 Singapore 13 5 Costerton Biofilm Center, Department of Immunology and Microbiology, University of 14 Copenhagen, DK- 2200, Denmark 15 6 These authors contributed equally to this work 16 17 * To whom correspondence should be addressed. 18 E-mail: (S.-S.C) chmchngs@nus.edu.sg, (M.G) mgivskov@sund.ku.dk 19 20 not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission. The copyright holder for this preprint (which was this version posted October 5, 2017. . https://doi.org/10.1101/198820 doi: bioRxiv preprint