Jebmh.com Original Research Article J Evid Based Med Healthc, pISSN - 2349-2562, eISSN - 2349-2570 / Vol. 8 / Issue 21 / May. 24, 2021 Page 1636 Assessment of Quality of Life in Patients with Chronic Kidney Disease on Maintenance Haemodialysis with Regard to Anaemia - A Descriptive Cross-Sectional Study at a Tertiary Hospital in Kuppam Uma M.A. 1 , Nagakiran K.V. 2 , Ashwin K. 3 , R. Lakshmi Visruja 4 1, 4 Department of General Medicine, P.E.S. Institute of Medical Sciences and Research, Kuppam, Andhra Pradesh, India. 2 Department of Orthopaedics, P.E.S. Institute of Medical Sciences and Research, Kuppam, Andhra Pradesh, India. 3 Department of General Surgery, P.E.S. Institute of Medical Sciences and Research, Kuppam, Andhra Pradesh, India. ABSTRACT BACKGROUND Anaemia is common among chronic kidney disease (CKD) patients. Quality of life (QOL) is a broad multidimensional concept and many factors affect QOL in CKD patients. This study attempted to measure QOL with varying levels of haemoglobin in CKD patients. METHODS The present study was a descriptive cross-sectional study done on CKD patients on maintenance haemodialysis (MHD) after ethical committee approval. All patients aged more than 18 years on MHD for at least 3 months were enrolled in the study. Patients were categorised into 4 separate groups as Hb 4 to < 6 g/dl, 6 to < 8 g/dl, 8 to < 10 g/dl and 10 - 12 g/dl. After obtaining informed consent, participants were given the study questionnaire - kidney disease quality of life (KDQOL) short form (SF - 36) TM V1 .2. RESULTS At different Hb levels, there were significant differences in the kidney symptom/ problem scores (P = 0.000), the burden of kidney disease scores (P = 0.000), the work satisfaction scores (P = 0.014) and the cognitive function scores (P = 0.000). About SF - 36, all of the physical domains were significantly different: physical function scores (P = 0.000), role physical scores (P = 0.045), pain scores (P = 0.000) and general health component scores (P = 0.004) at different Hb levels. For mental domain components, the differences between four groups of Hb levels were significant in the variety of quality of life domains: emotional wellbeing score (P = 0.006), role emotion scores (0.000), social function scores (P = 0.000) and energy/fatigue scores (0.026). CONCLUSIONS KDQOL, SF - 36 showed that the QOL scores are strongly related to Hb concentrations. The higher scores in various quality of life domains were mostly associated with higher Hb levels in the KDQOL - SF scores. Efforts to optimize haemoglobin in CKD patients may show QOL improvement. KEYWORDS Chronic Kidney Disease, Haemodialysis, Anaemia, Quality of Life Corresponding Author: Dr. R. Lakshmi Visruja, # 303, Hill View Apartment, PESIMSR Campus, Kuppam - 517425, Andhra Pradesh, India. E-mail: visruja@gmail.com DOI: 10.18410/jebmh/2021/309 How to Cite This Article: Uma MA, Nagakiran KV, Ashwin K, et al. Assessment of quality of life in patients with chronic kidney disease on maintenance haemodialysis with regard to anaemia-a descriptive cross -sectional study at a tertiary hospital in Kuppam. J Evid Based Med Healthc 2021;8(21):1636-1641. DOI: 10.18410/jebmh/2021/309 Submission 02-02-2021, Peer Review 13-02-2021, Acceptance 02-04-2021, Published 24-05-2021. Copyright © 2021 Uma M.A. et al. This is an open access article distributed under Creative Commons Attribution License [Attribution 4.0 International (CC BY 4.0)]