RESEARCH
Current Research
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Meets learning need codes 3000, 3010, 9010, and 9020
Low Energy Reporting May Increase in
Intervention Participants Enrolled in Dietary
Intervention Trials
BETTE CAAN, DrPH; RACHEL BALLARD-BARBASH, MD, MPH; MARTHA L. SLATTERY, PhD, MPH, RD; JOAN L. PINSKY, MA;
FRANK L. IBER, MD; DONNA J. MATESKI, MS, RD; JAMES R. MARSHALL, PhD; ELECTRA D. PASKETT, PhD; MOSHE SHIKE, MD;
JOEL L. WEISSFELD, MD; ARTHUR SCHATZKIN, MD; ELAINE LANZA, PhD
ABSTRACT
Objective To examine differences in low energy intake re-
porting between intervention and control groups during a
dietary intervention trial.
Design Retrospective data analysis from a subcohort of
participants in the Polyp Prevention Trial (PPT), a
4-year, multisite, randomized, controlled dietary inter-
vention trial. Intervention consisted of educational mate-
rial and counseling sessions supporting a low-fat, high-
fiber diet. Baseline and annual demographics, behavioral
characteristics, energy intake (EI) based on self-reported
4-day food records, and height and weight of participants
were collected at baseline and annually. Basal metabolic
rate (BMR) was estimated (using the Schofield equation)
to calculate EI/BMR.
Subjects Of the 443 participants (302 male, 141 female) at
baseline, 195 (43.3%) were younger than 60 years, and 394
(91%) were white. At Year 4, 383 participants remained:
186 (122 men, 64 women) in the intervention group, and 197
(133 men, 64 women) in the control group.
Statistical Analyses Using either paired t tests or analysis of
variance, the differences between the means for EI, weight,
and EI/BMR were compared at baseline, Year 1, and Year 4
for the participants who remained at Year 4. The Goldberg
EI/BMR cutoff value of 1.06 (for plausible EI) identified
participants who reported low EI. Linear regression was
used to quantify the association of various risk factors to
EI/BMR and for multivariate analyses within groups.
2
B. Caan is a senior research scientist with Kaiser Per-
manente Medical Care Program of Northern California,
Division of Research, Oakland. R. Ballard-Barbash is
associate director, Applied Research Program with the
National Cancer Institute, Division of Cancer Preven-
tion and Control, Applied Research Program, Bethesda,
MD. M. L. Slattery is a professor with University of
Utah School of Medicine Department of Family and Pre-
ventive Medicine, Salt Lake City. J. L. Pinsky is a se-
nior systems analyst with Westat, Rockville, MD. F. L.
Iber is Emeritus professor of Medicine, Stritch School of
Medicine, Loyola University, Chicago and volunteer
clinic director, Gastroenterology Clinic, Edward Hines,
Jr. Veterans Administration Hospital, Hines, IL. D. J.
Mateski at the time of the study was a research nutri-
tionist with the Gastroenterology Service, Walter Reed
Army Medical Center, Washington, DC. J. R. Marshall
is senior vice president for Cancer Prevention and Popu-
lation Sciences, Roswell Park Cancer Institute, Buffalo,
NY. E. D. Paskett is currently Marion N. Rowley Profes-
sor of Cancer Research with the School of Public Health,
College of Medicine and Public Health, The Ohio State
University, Columbus; at the time of this study she was
with the Department of Public Health Services, Wake
Forest University School of Medicine, Winston-Salem,
NC. M. Shike is director, MSK Cancer Prevention and
Wellness Program with Memorial Sloan-Kettering Can-
cer Center, Memorial Hospital for Cancer & Allied Dis-
eases, New York, NY. J. L. Weissfeld is associate profes-
sor of Epidemiology with the Department of Epidemiology,
University of Pittsburgh, Pittsburgh, PA. A. Schatzkin
is chief, Nutritional Epidemiology Branch, Division of
Cancer Epidemiology and Genetics with the National
Cancer Institute, Division of Cancer Epidemiology and
Genetics/Nutritional Epidemiology Branch, Rockville,
MD. E. Lanza is senior investigator with the National
Cancer Institute Cancer Prevention Studies Branch,
Bethesda, MD.
Address correspondence to: Bette Caan, DrPH, Divi-
sion of Research, Kaiser Permanente Medical Care Pro-
gram, 2000 Broadway, Oakland, CA 94612.
E-mail: bjc@dor.kaiser.org
Presented in part at the Fourth International Confer-
ence on Dietary Assessment Methods, Tucson, AZ, Sep-
tember 19, 2000, and published in abstract form in the
proceedings.
Copyright © 2004 by the American Dietetic
Association.
0002-8223/04/10403-0012$30.00/0
doi: 10.1016/j.jada.2003.12.023
© 2004 by the American Dietetic Association Journal of THE AMERICAN DIETETIC ASSOCIATION 357