_____________________________________________________________________________________________________ *Corresponding author: E-mail: m_hamayon@yahoo.com; Journal of Pharmaceutical Research International 31(4): 1-13, 2019; Article no.JPRI.51341 ISSN: 2456-9119 (Past name: British Journal of Pharmaceutical Research, Past ISSN: 2231-2919, NLM ID: 101631759) Preliminary Phytochemical Profile, in vitro Antioxidant and Sun Protective Activities of Alhagi pseudalhagi and Elaeagnus angustifolia L. Mohammad Humayoon Amini 1* , Amina Ahmady 2 , Aqa Mohammad Zhakfar 2 , Mohammad Nasim Sediqi 1 and Gulalai Babak 2 1 Department of Pharmacognosy, Faculty of Pharmacy, Kabul University, Kabul, Afghanistan. 2 Department of Pharmaceutics, Faculty of Pharmacy, Kabul University, Kabul, Afghanistan. Authors’ contributions This work was carried out in collaboration among all authors. Authors MHA, AMZ and MNS collected the plants raw materials. Authors MHA and AA conceived, designed and performed the experiments, analyzed and interpreted the data and drafted the manuscript. All authors read, revised and approved the final version of the manuscript before submission. Article Information DOI: 10.9734/JPRI/2019/v31i430308 Editor(s): (1) Dr. Q. Ping Dou, Professor, Barbara Ann Karmanos Cancer Institute, Departments of Oncology, Pharmacology and Pathology, School of Medicine, Wayne State University, USA. Reviewers: (1) Maria Bintang, IPB University, Indonesia. (2) Moldovan Zenovia, University of Bucharest, Romania. Complete Peer review History: http://www.sdiarticle4.com/review-history/51341 Received 08 July 2019 Accepted 16 September 2019 Published 12 November 2019 ABSTRACT Background and Objectives: Alhagi pseudalhagi and Elaeagnus angustifolia are among the medicinal plants used traditionally in Afghanistan. The aim of present work was to study A. pseudalhagi herbs and E. angustifolia leaves for their preliminary phytochemical profile, total phenolic content (TPC), total flavonoid content (TFC), in vitro antioxidant activity and sun protective factor (SPF). Methods: Alhagi pseudalhagi herb crude extract (APCE) and E. angustifolia leaves crude extract (EACE) were prepared using Soxhlet apparatus. Standard qualitative phytochemical tests were performed to detect various phytochemicals in the crude drugs. Both of APCE and EACE were purified as per previously described method to obtain A. pseudalhagi herb purified extract (APPE) and E. angustifolia leaves purified extract (EAPE). The TPC, TFC, and SPF of the extracts were determined, Following prescribed methods. To evaluate in vitro antioxidative potential of the Original Research Article