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Abbreviation: LED, light emitting diode
Introduction
Diabetes is a disease that encompasses various metabolic disorders
in which the blood glucose index gets high. This disease can cause
wounds in the feet caused by a set of alterations in the lower limbs,
being injuries in the nerves, alterations in the arteries, the reduction of
immunity and, sometimes, alterations in the bony anatomy of the feet.
This consequence is called diabetic foot.
1
A skin lesion triggers a series of biochemical events aimed at
restoring vascular and cellular integrity. During the healing process,
the tissue is vulnerable to several factors that may disrupt it. The
failure of any phase of the repair process sequence may prevent
healing and lead to signifcant morbidity, resulting in costs.
2
The tissue
neoformation induction system aims to treat patients who present
ulcers from various diseases and do not respond well to conventional
treatments, it’s seen as a new form of phototherapy, but with reduced
costs due to the use of high brightness LED in place of LASER
The number of people who have chronic wounds in Brazil has
increased in recent years. Minimizing the suffering of these people is
what motivated the development of anequipment capable of replacing
the conventional method of treatment, since it can substantially
accelerate scarring processes at a low cost. This equipment is called
RAPHA, a mobile tissue neoformation system based on the principles
of phototherapy which aims to aid in the healing of wounds, along
with a blade made of latex.
Discussion
The treatment of 4 participants of the research using silver foam
and 6 other participants treated using the latex blade associated to
the use of LED for 30 minutes were compared. The clinical fndings
were analyzed qualitatively and quantitatively, demonstrating that the
results obtained by the group treated with the LEDs were higher than
those obtained by the foam treated group.
3
This fact suggests that the
tissue neoformation induction system presented here, is characterized
by an effective treatment option for diabetic foot ulcer due to the high
potential in inducing healing.
After the ulcer closes, remodeling and maturation of the formed
scar occurs. This phase takes months or years, and involves reducing
the number of cells and blood fow in scar tissue, reformulating and
improving the components of collagen, and reabsorption of water.
Maturation is responsible for increased tensile strength (maximum
80% of normal skin force) and decreased scar size.
4
In this way, it can be seen that wound healing has been studied
with several covering techniques to Hevea brasiliens is better
treat the wound and demonstrate healing effectiveness. The use
of new coatings, among them the use of latex of in animals
5–7
and
humans.
3,8–13
Conclusion
Therefore, the method of treatment of ulcers through LEDs
associated with a latex blade is shown as a positively differentiated
approach to those already presented in the literature and currently
used in research participants with ulcers in the lower limbs. The
RAPHA equipment is intended to treat ulcers presented in external
regions of the body which may interact with the light provenient from
LEDs, such as diabetic ulcers, which is a chronic wound that occurs in
people who, for various reasons, have had a complication of diabetes,
pressure ulcers which are very common in bedridden or mobility
impaired patients as it is caused by too much pressure in a region of
the body that ultimately damages the skin.
Acknowledgements
The research group thanks the federal entities that supported
Adv Tissue Eng Regen Med Open Access. 2018;4(1):1‒2. 1
© 2018 Agnello et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which
permits unrestricted use, distribution, and build upon your work non-commercially.
The use of phototherapy for healing treatments:
study of new techniques for tissue neoformation
Volume 4 Issue 1 - 2018
Renato Cesar da Silva Agnello, Suellia
Rodrigues Fleury Rosa, Malrio Fabríclcio
Fleury Rosa, Bruno da Costa Motta
Biomedical Engineering Laboratory, University of Brasilia, Brazil
Correspondence: Renato CS Agnello, Graduation
student of Electronic Engineering, Biomedical Engineering
Laboratory, University of Brasilia, Quadra 107, Lote 18, Casa
11, Condomíclnio Village Saint Clair, Brasícllia, Brazil, Tel
+5561999405107, Email ragnello19@gmail.com
Received: September 18, 2017 | Published: January 08, 2018
Abstract
According to the Brazilian Association of Endocrinology and Metabolism, diabetes, or
Diabetes Mellitus, is a chronic, autoimmune disease, characterized by the deficiency
of insulin production by the body. The problem involves the metabolism of glucose in
the blood and can be presented in several ways. The best known types of diabetes are
1 and 2. Beta- cell failure in the pancreas characterizes the first, which affects children
and adolescents more often. Type 2 diabetes, whose genetic load is much higher,
occurs due to resistance to insulin action, with obesity as one of the main triggering
factors. The other forms of diabetes can be manifested by anatomical lesions in the
pancreas, due to several toxic aggressions, by infections, chemical compounds, among
others. A very common consequence of diabetes it’s a formation of skin wounds due
to metallic disorders, these wounds can be very aggressive and diminish the quality
of life of the patients. Anequipment based on phototherapy associated with a latex
blade was developed as an alternative treatment for skin wounds, the equipment works
directly on the neoformation of the wounded tissue, accelerating the scarring process
at a low cost.
Keywords: tissue neo formation, new technique, low cost, LED
Advances in Tissue Engineering and Regenerative Medicine
Mini Review
Open Access