76 NJOG / VOL 15 / NO. 1 / Issue 30/ Jan - Jun, 2020 Nep J Obstet Gynecol. 2020;15(30):76-78 Brief Communication Management of COVID-19 Infected Patients in Pregnancy and Puerperium Basant Sharma 1 , Ganesh Dangal 2 , Bandana Khanal 1 , Siddeshwar Angadi 3 1 Department of Obstetrics and Gynecology, Chitwan Medical College, Bharatpur 2 Department of Obstetrics and Gynecology, Kathmandu Model Hospital, Kathmandu 3 School of Nursing, Chitwan Medical College, Bharatpur Received: May 15, 2020 Accepted: May 31, 2020 ABSTRACT COVID-19 is a pandemic affecting every group of people. Pregnancy itself is a partially immune compromised state, so chance of aggravation of symptom supposed to be more in pregnancy. Prevention is the best way to get away from this disease. Good hygiene, supportive care and possible mechanical ventilation for severe case are required. There is no proven role of antibiotic, antiretroviral and steroids. There is no proven vertical transmission. Baby has to be kept in isolation and breast milk can be expressed and given to newborn. Keywords: COVID-19, pandemic, pregnancy. Citation : Sharma B, Dangal G, Khanal B, Angadi S. Management of COVID-19 Infected Patients in Pregnancy and Puerperium. Nep J Obstet Gynecol. 2020;15(30):76–78. DOI: 10.3126/njog.v15i1.29347 CORRESPONDENCE Dr Basant Sharma Department of Obstetrics and Gynecology, Chitwan Medical College, Chitwan Email:sharma.basant@cmc.edu.np; Phone: +977-9851220907 INTRODUCTION After the emergence SARS-CoV-2 virus the COVID-19 has become pandemic affecting all age groups of people. Pregnancy itself is a partially immunosuppressed state and any viral or bacterial pneumonia can be life-threatening during pregnancy. 1 This disease causes more adverse effects in pre- existing diseases like diabetes, hypertension, COPD and cancer. 2 Other corona viruses like Severe Acute Respiratory (SARS-CoV) and middle-east respiratory syndrome (MERS-CoV) are from same family. There are no definite data of mortality or morbidity from COVID-19 but there are reports of mortality of around 37%in Middle-East Respiratory Syndrome (MERS-CoV) and as high as 25% in Severe Acute Respiratory (SARS-CoV) pregnant women. 3,4 Few clinical experiences from world have shown that iatrogenic preterm delivery could have been increased but requires more data to be statistically significant. Emerging evidence now suggests that vertical transmission is probable, but the proportion of pregnancies affected and the significance to the neonate has yet to be proven. Effect on early pregnancy is unknown. Rate of spontaneous miscarriages or intrauterine fetal deaths are not clear till date. Teratogenicity of virus to fetus are not found in these limited studies. 5, 6 Preventive measures during pregnancy Frequent hand washing, avoiding outdoor works, crowded places and social gathering are utmost for pregnant lady. Contact with people from hot spot areas is to be restricted. Immediate consultation with obstetrician and regular temperature monitoring in presence of symptoms like dyspnea, fever, and cough are essential. Pregnant lady with travel history to hot spot area and clinical suspicion of infection should be kept in isolation room with negative pressure for at least two weeks; and psychological support is to be given to avoid depression and anxiety in pregnant lady. 4,7