Int J Front Sci Post-operative Pain in Abdominal Surgery Patients Original Article 26 Volume 2 (Issue 2) Post-Operative Pain Comparison between Peri-Operative Bupivacaine Infiltration Vs Post-Operative Opioids Analgesics in Patient Undergoing Abdominal Surgery in First 6 Hours Syeda Hina Zahra 1* , Qudrat Ullah 1 , Usman Ali Rehman 1 , Asif Hanif 2 and Sami Ullah Bhatti 1 1. Department of Surgery, Gulab Devi Postgraduate Medical Institute Lahore, Pakistan 2. Department of Biostatistics, Gulab Devi Postgraduate Medical Institute Lahore, Pakistan *Corresponding author: haniashah2228@gmail.com Abstract: Background: To compare between opioids and wound infiltration to reduce post-operative pain in abdominal surgery in first 6 hours, in appropriate treatment, contraindications of treatment and increase mortality of patients. This article presents novel approach to surgical site infiltration techniques and intravenous opioids for abdominal surgery to reduce pain. The main aim of this study is optimal patient comfort rather than reduce pain intensity, reduction offside effects is also an important goal in pain management. Methodology: Data was collected from surgical department of Gulab Devi Chest Hospital. During abdominal surgery bupivacaine was given to some patients while other were managed by post- operative opioids and by using designed performa it is concluded that which one of them is better method for post-operative pain management. Results: This is the descriptive study conducted in Gulab Devi Hospital Lahore.in this study, in this study minimum age of the patients was 14 and maximum age of the patients was 80. The mean age was 32.16+12.32 years. In this study out of total 100 patients, 18(18.00%) were male patients and 82(82.00%) were females. Female gender predominated in this study. in this study, p-value is 0.00 (<0.05%) so pain relieving chances of bupivacaine infiltration as moderate pain scale were 84% and in distracting pain scale chances in bupivacaine infiltration were 16%.But pain relieving chances of opioids as moderate pain scale were 12.24 % and in distracting pain scale chances in opioids were 87.75%.so peri-operative pain management by bupivacaine infiltration is better than post –operative opioids management in patients undergoing abdominal surgery. Conclusion: According to my research bupivacaine wound infiltration is better method for post- operative pain management in abdominal surgeries. Our study was conducted at Gulab Devi Hospital and Services Hospital in an area of pain management by opioids and infiltration, which may limit the applications of our findings in area of pain management by opioids and infiltration prevalence. Key words: Bupivacaine, opioids, analogue pain scale, abdominal surgery ______________________________________________________________________________ Introduction: Abdominal surgery is defined as surgery pertaining to the contents of the abdominal cavity, its walls and orifices. Pain is a distressing feeling often caused by intense or damaging stimuli, such as stubbing a toe, burning a finger, putting alcohol on a cut, or bumping the "bone". Postoperative pain is