_____________________________________________________________________________________________________ *Corresponding author: E-mail: robinsonohanador@yahoo.com; Journal of Advances in Medical and Pharmaceutical Sciences 18(1): 1-10, 2018; Article no.JAMPS.40957 ISSN: 2394-1111 Prevalence of Renal Dysfunction and Its Relationship to CD4 and TNF Alpha of HIV Positive Individuals on Anti-retroviral Therapy in Port Harcourt Beatrice E. Imananaghe-Amene 1 , Ohanador Robinson 2* , Josephine Iruolagbe 1 and A. W. Obianime 1 1 Department of Pharmacology, University of Port Harcourt, Nigeria. 2 Department of Biochemistry, University of Port Harcourt, Nigeria. Authors’ contributions This work was carried out in collaboration between all authors. Author OR designed the study, performed the statistical analysis, wrote the protocol and wrote the first draft of the manuscript. Authors BEIA and JI managed the analyses of the study. Author AWO managed the literature searches. All authors read and approved the final manuscript. Article Information DOI: 10.9734/JAMPS/2018/40957 Editor(s): (1) Dr. Amr Ahmed El-Arabey, Pharmacology & Toxicology Department, Al-Azhar University, Egypt & University of Science and Technology of China (USTC), China. (2) Dr. Jinyong Peng, Professor, College of Pharmacy, Dalian Medical University, Dalian, China. (3) Dr. Nissar Darmani, Professor, Pharmacology, Associate Dean for Basic Medical Sciences and Research, Chair, Basic Medical Sciences, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, California. Reviewers: (1) Roberta Termini, Italy. (2) Henrique Pott Junior, Federal University of São Paulo, Brazil. (3) Tatsuo Shimosawa, International University of Health and Welfare, Japan. (4) Godfrey Mutashambara Rwegerera, University of Botswana, Botswana. (5) Iorhen Ephraim Akase, Lagos University Teaching Hospital, Nigeria. Complete Peer review History: http://www.sciencedomain.org/review-history/26418 Received 23 March 2018 Accepted 29 August 2018 Published 27 September 2018 ABSTRACT Background: Despite the success of anti-retroviral drugs, renal impairment remains one of the most significant complications of HIV. This study aimed to evaluate the prevalence of renal impairment and its association with age, gender, CD4 and TNF alpha of HIV positives in the University of Port Harcourt Teaching Hospital (UPTH). Original Research Article