119 Copyright © 2011, IGI Global. Copying or distributing in print or electronic forms without written permission of IGI Global is prohibited. Chapter 6 DOI: 10.4018/978-1-60960-619-0.ch006 Peter H. Verburg VU University Amsterdam, The Netherlands Jan Peter Lesschen Alterra Wageningen UR, The Netherlands Eric Koomen VU University Amsterdam, The Netherlands Marta Pérez-Soba Alterra Wageningen UR, The Netherlands Simulating Land Use Policies Targeted to Protect Biodiversity with the CLUE-Scanner Model ABSTRACT This chapter presents an integrated modelling approach for assessing land use changes and its effects on biodiversity. A modelling framework consisting of a macro-economic model, a land use change model, and biodiversity indicator models is described and illustrated with a scenario study for the European Union. A reference scenario is compared to a scenario in which a number of possible policies for conservation and protection of biodiversity are assumed to have been implemented. The results are evaluated by an indicator of the habitat quality for biodiversity and an indicator of landscape connectivity. The results illustrate that land use change has spatially diverse impacts on biodiversity. The effectiveness of the assumed policies is region and context dependent. The modelling framework can thus provide ex-ante assessments of policies and identify critical regions for biodiversity conservation and assist in targeting policies and incentives to protect biodiversity in vulnerable areas.