CASE REPORT Open Access
Diagnostic ambiguity of aseptic necrobiosis
of a uterine fibroid in a term pregnancy: a
case report
Julius Sama Dohbit
1,2
, Esther Ngo Um Meka
1,2
, Joel Noutakdie Tochie
3*
, Igor Kamla
3
, Celestin Danwang
3
,
Frank-Leonel Tianyi
4
, Pascal Foumane
1,2
and Gervais Ondobo Andze
3,5
Abstract
Background: Uterine fibroids are the most common uterine tumours in females of reproductive age. During
pregnancy, uterine fibroids may be complicated by aseptic necrobiosis. We herein report an ambiguous clinical
presentation of uterine fibroids in pregnancy and discuss the diagnostic challenges encountered in our resource-
constraint setting.
Case presentation: A term pregnant Cameroonian woman was admitted to our maternity unit with clinical
findings suggestive of a strangulated umbilical hernia. She underwent an emergency caesarean section which
fortuitously revealed aseptic necrobiosis of a uterine fibroid, managed within the same surgical intervention by
myomectomy. Her post-operative course was uneventful.
Conclusion: The authors highlight the need for a high index of suspicion by healthcare providers, as well as the
need for a multidisciplinary approach for a favourable maternal and foetal outcome.
Keywords: Uterine fibroid, Leiomyoma, Pregnancy, Aseptic necrobiosis, Red degeneration
Background
Leiomyomas (uterine fibroids) are the most common be-
nign tumors of the uterus [1]. They are very common,
affecting 40% of women of reproductive age and their
frequency increases with age, from a prevalence of 50%
at age 35 years, to 80% at age 50 years [1]. An increase in
the age of first pregnancy from 24 years in 1978 to 30
years in 2012 has seen an increase in the occurrence of
uterine fibroids in pregnancy [2, 3]. Pregnant women
with uterine fibroids are at an increased risk for compli-
cations such as; miscarriages, preterm labour, malpresenta-
tion, labor dystocia, cesarean sections and postpartum
haemorrhage [4, 5]. Uterine fibroids often increase in size
during pregnancy, this increases their risk for complications
such as ‘red degeneration’ or aseptic necrobiosis [5] and
leads to frequent diagnostic ambiguity of obstetrical or gy-
naecological pathologies in resource-challenge settings [6].
Herein, we report the case of an aseptic necrobiosis of a
uterine fibroid mimicking a strangulated umbilical hernia
on a term pregnancy.
Case presentation
A 35-year-old G
2
P
0010
Cameroonian student at 39-weeks
pregnancy was referred to the surgical unit of the
Yaounde Gynaeco-Obstetrics and Paediatric Hospital for
the management of a strangulated umbilical hernia. She
had a sudden onset of localized umbilical pain three
hours prior to consultation. The pain was of moderate
intensity, crampy in character, aggravated by walking,
without any change in bowel movement and no vomit-
ing. An abdominal ultrasound scan revealed a parietal
defect of the umbilicus measuring 55 mm in diameter
with a poorly vascularised hypoechoic mass (doppler
scan) measuring 50 × 30 × 37 mm, 29.6 ml in volume. In
addition, the foetus was viable with a normal biophysical
score and a good concordance between clinical and
sonographic dating of gestational age. Hence, she was
* Correspondence: joeltochie@gmail.com
3
Departement of Surgery and Specialities, Faculty of Medicine and
Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon
Full list of author information is available at the end of the article
© The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0
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reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to
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(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Dohbit et al. BMC Pregnancy and Childbirth (2019) 19:9
https://doi.org/10.1186/s12884-018-2154-x