Case Report / Olgu Sunumu Kikuchi-Fujimoto Disease Associated with Aseptic Meningitis: A Case Report 11 Abstract Kikuchi-Fujimoto Disease is usually a rare, self limit- ing, benign disease causing fever, neutropenia and cervical lymphadenopathy. It is especially seen in young Asian women, rarely in children. A case of Kikuchi-Fujimoto Disease in a female Bangladeshian child with aseptic meningitis is presented from Turkey. She was admitted with fever but had no pathological lymphadenopathies. Her complicated aseptic meningitis was treated successfully with short term steroid therapy. (J Pediatr Inf 2011; 5: 77-9) Key words: Kikuchi-Fujimoto Disease, meningitis, lympadenopathy, fever Özet Kikuchi-Fujimoto hastalığı ateş, nötropeni ve servikal lenfadenopatiyle seyreden ve özellikle genç Asyalı kadınlarda görülen bir hastalıktır. Çocuklukta nadir olarak görülür. Aseptik menenjit ile başvuran Bengaldeş’li bir kız hastada saptanması nedeniyle sunulmaktadır. Hasta inatçı ateşle müracaat etmesine karşın, lenfadenopatisi yoktur. Oluşan komplikasyon- lu aseptic menenjit tablosu kısa süreli steroid ile tedavi edilmiştir. (J Pediatr Inf 2011; 5: 77-9) Anahtar kelimeler: Kikuchi-Fujimoto, lenfadenopa- ti, menenjit, ateş Geliş Tarihi: 06.12.2010 Kabul Tarihi: 07.02.2011 Correspondence Address: Yazışma Adresi: Dr. Zafer Arslan TOBB-ETU Hastanesi, Çocuk Sağlığı ve Hastalıkları Bölümü, Ankara, Turkey Phone: +90 312 241 39 80 E-mail: zarslan_99@yahoo.com doi:10.5152/ced.2011.27 Aseptik Menenjitle Birlikte Görülen Bir Kikuchi-Fujimoto Hastalığı Vakası 77 Zafer Arslan, Özge Uysal, Ali Özön, Abbas Rad, Aygün Atacanl ı , Nejat Akar, Şükrü Cin, Murat Sümer TOBB-ETU Hastanesi, Çocuk Sağl ı ğı ve Hastal ı kları Bölümü, Ankara, Turkey Introduction Kikuchi-Fujimoto Disease is usually a rare, self limiting, benign disease, causing fever neu- tropenia and cervical lymphadenopathy, seen especially in young Asian women but rarely in children (1). If it is not considered in patients with fever of unknown origin with cervical lymphadenopathy, this may result in unneces- sary invasive tests. Although self limiting, rare fatal cases were reported (2). Case A 11 year old Bangladeshian female child who lived in Ankara/Turkey because of her father’s occupation presented with persistent and intermittent fever up to 40°C of twelve days duration. She had fever and sore throat since the beginning of disease. The patient was given benzatine penicillin (1 200 000 IU) once intra- muscularly and ceftriaxone for the following two days in a local hospital. Foreign travel included a brief return to Bangladesh, a trip to Canada 6 months previously and a visitto a small cattle farm near Ankara 2 weeks previously. She appeared well; but her temperature was 39°C. There were only two non-tender lymph- adenopathies 1x1, 1x0.5 cm size in the right posterior cervical region. She had no hepato- splenomegaly. The rest of the physical exami- nation was normal. Laboratory revealed low white cell count of 3700mm 3 with neutrophils 48%, low platelet count 141 000/mm 3 , and high lactic dehydroge- nease (LDH) 862 IU/L. C Reactive protein was 9 mg/dl and sedimentation rate was 36 mm/hr. Biochemical profile, thyroid function tests, quan-