International Journal of Research in Medical Sciences | June 2019 | Vol 7 | Issue 6 Page 2240 International Journal of Research in Medical Sciences Agarwal A et al. Int J Res Med Sci. 2019 Jun;7(6):2240-2245 www.msjonline.org pISSN 2320-6071 | eISSN 2320-6012 Original Research Article Pulmonary function test in patients of type 2 diabetes mellitus Amit Agarwal 1 , Ankit Grover 2 *, Amresh Agarwal 2 INTRODUCTION We are today witnessing a pandemic of diabetes mellitus (DM), globally and nationally. DM and its complications have become the most important contemporary and challenging health problems. There are 347 millions diabetics worldwide. 1 In India more than 67 millions have been affected. India has become the diabetic capital of world. WHO projects that diabetes will be the 7th leading cause of death in 2030. 1 Diabetes mellitus is a major, rapidly growing public health care problem. It is increasing in incidence, and brings with it long term complications. 2 Diabetes mellitus is an incurable life-long disease, involving multiple systems, and with devastating complications which end up in severe disability and death. 3 Diabetes mellitus complications are mainly the consequences of macro- vascular and micro-vascular damage. 4 Chronic hyperglycemia of diabetes mellitus is associated with continuing damage, dysfunction, and failure of various organs, especially the eyes, kidneys, nerves, heart, and blood vessels. Diabetes is not associated with any specific pulmonary symptom and hence periodic screening for lung disease is 1 Department of Gastroenterology, MMU Hospital, Mullana, Ambala, Haryana, India 2 Department of Medicine, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, India Received: 23 March 2019 Accepted: 03 May 2019 *Correspondence: Dr. Ankit Grover, E-mail: angrover@gmail.com Copyright: © the author(s), publisher and licensee Medip Academy. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. ABSTRACT Background: We are today witnessing a pandemic of diabetes mellitus (DM), globally and nationally. DM and its complications have become the most important contemporary and challenging health problems. Diabetes is not associated with any specific pulmonary symptom and hence periodic screening for lung disease is not done in diabetic patients. However, an extensive microvascular circulation and an abundant connective tissue in the lung raise the possibility that the lung may also be a target organ in diabetic patients. The aim and objectives were to study the pulmonary function of individual with type 2 diabetes mellitus patients by performing spirometry. Methods: Study included non-smoker diabetic patients, who had no history of respiratory disease, were selected for this study and undergone pulmonary function test by spirometry. The study was conducted at department of General Medicine Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, India. Results: Present study, author found that there was significant derangement in the spirometric readings in the diabetic patients. The FEV1/FVC values further declines as the duration of diabetes increased. Conclusions: Spirometric values (FVC, FEV1, FEV1/FVC) were consistently lower in subjects with type 2 diabetes mellitus. The effect on FVC predicted % was found to be more pronounced in subjects whose duration of DM was more than 5 years. Keywords: Diabetes mellitus, FEV1, FVC, FEV1/FVC, Spirometry DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20192505