July 2018 · Volume 7 · Issue 7 Page 2899 International Journal of Reproduction, Contraception, Obstetrics and Gynecology Devi KR et al. Int J Reprod Contracept Obstet Gynecol. 2018 Jul;7(7):2899-2903 www.ijrcog.org pISSN 2320-1770 | eISSN 2320-1789 Original Research Article A study of congenital anomalies in a tertiary care hospital in North East region, India Kangjam Radhesana Devi 1 , R. K. Praneshwari Devi 1 *, Jyoti Priya 1 , Ahanthembi Sanaton 2 , Leimapokpam Roshan Singh 1 , Lalhlimpuii Murray 1 INTRODUCTION Congenital anomalies are defined as structural or functional anomalies that occur during intrauterine life. These anomalies result from defective embryogenesis or intrinsic abnormalities in process of development and are prenatal in origin. Birth defects can be isolated abnormalities or part of a syndrome and are one of the most important cause of neonatal morbidity and mortality both in developed and developing countries. 1 In developing country like India due to the high incidence of infectious diseases, nutritional disorders and social stress, the development defects are often over shadowed, but the present scenario ABSTRACT Background: Congenital anomalies are important cause of morbidity and mortality in newborns and are defined as structural and functional abnormalities including metabolic disorders present at birth. These defects are of prenatal origin resulting from defective embryogenesis or intrinsic abnormalities in the process of development and are associated with various risk factors. Methods: Our study is a cross-sectional study done at Regional Institute of Medical Sciences, Imphal over period of one and half years from May 2016 to October 2017. Aim of study was to find out incidence of congenital anomalies and proportions of different types of congenital anomalies. Outcome was studied in relation to maternal age, religion, parity, gestational age, sex of baby, outcome and birth weight of baby. Results: Total numbers of congenital anomalies were 91 out of 13658 births. Incidence of congenital anomalies was 0.66%. Most common congenital anomaly was cleft lip (17.6%) followed by CTEV (13.2%) and was more common among male term babies. These were most common in 18-24 years of maternal age group (34.1%) followed by 30-34 years (26.4%) and among women of parity P0-P2. Conclusions: Congenital malformations are a major cause of still births and infant mortality. A level II targeted scan should be done at 18-20 weeks to find out anomalies and reduce the prevalence. There should be widespread education in the community regarding the common congenital malformations, their outcomes and possible available modes of treatment. Keywords: Anomalies, Newborn, Targeted scan 1 Department of Obstetrics and Gynaecology, Regional Institute of Medical Sciences, Imphal, Manipur, India 2 Department of Obstetrics and Gynaecology, Jawaharlal Nehru Institute of Medical Sciences, Imphal, Manipur, India Received: 06 May 2018 Revised: 23 May 2018 Accepted: 30 May 2018 *Correspondence: Dr. R. K. Praneshwari Devi, E-mail: praneshwarirk1@gmail.com Copyright: © the author(s), publisher and licensee Medip Academy. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20182903