HISTORICAL PAPER QUAGLINO’S 1867 CASE OF PROSOPAGNOSIA Sergio Della Sala 1 and Andrew W. Young 2 ( 1 Department of Psychology, University of Aberdeen, Scotland; 2 Department of Psychology, University of York, England) Antonio Quaglino was professor of Ophthalmology in Pavia, and later in Milan when the University of Pavia was closed because of the war between Italy and Austria. He died in 1894 aged 76 (Guaita and Rampoldi, 1894). He was the author of 61 scientific papers, one of which has some importance in Neuropsychology. In 1867 he reported on the case of a patient, Mr. LL, who following a right hemisphere stroke, showed a clear prosopagnosia coupled with inability to recognise buildings in his own town and colour blindness. This report was accompanied by a commentary by Gian Battista Borelli, who was LL’s physician at the time he suffered the stroke and later founder and editor-in-chief of the “Giornale D’Oftalmologia Italiano”, the ophthalmology journal in which the report was published. Borelli’s commentary provides further details pertaining to some of the points made by Quaglino, though in places it has a different theoretical emphasis. This was not the first observation of a patient’s inability to recognise familiar faces. Wigan (1844) had briefly described a man with an “utter inability to remember faces. He would converse with a person for an hour, but after an interval of a day could not recognise him again. Even friends, with whom he had been engaged in business transactions, he was unconscious of ever having seen.” According to Wigan (1844), “He was quite incapable of making a mental picture of anything, and it was not till he heard the voice, that he could recognise men with whom he had constant intercourse”. However, Quaglino’s case is of special interest because it anticipates and bears so directly on points that have arisen in later discussions of the topic of acquired impairments of face recognition. The report has been cited occasionally (e.g. De Renzi, 1982; Benton, 1990; Davidoff and Landis, 1990; Muggia and Trivelli, 1992; Young and van de Wal, 1996), but never translated. Here, we provide a translation of an abridged version of the paper, including its main empirical and theoretical content, but omitting most of its discursive material. We add a summary of Borelli’s commentary, and a brief discussion of the paper’s contribution. LEFT HEMIPLEGIA WITH CORTICAL BLINDNESS – RECOVERY – TOTAL LOSS OF COLOUR PERCEPTION AND OF MEMORY FOR THE CONFIGURATION OF OBJECTS Clinical observation by Antonio Quaglino Gall maintained that the brain is a collection of many organs subsuming different functions. He was positing a physiological hypothesis later to be Cortex, (2003) 39, 533-540