MANUSCRIPT ACCEPTED ACCEPTED MANUSCRIPT 1 Altered Decorin Leads to Disrupted Endothelial Cell Function: A Possible 1 Mechanism in the Pathogenesis of Fetal Growth Restriction? 2 3 Chui A 1 , Murthi P 2,3 , Gunatillake T 1,3 , Brennecke S.P 2,3 , Ignjatovic V 4,5,6 , Monagle P.T 4 4,5,6 , Whitelock J.M 7 , and Said J.M 1 5 6 1 NorthWest Academic Centre, The University of Melbourne and Sunshine Hospital, St 7 Albans 3021, Australia. 2 Department of Perinatal Medicine, Pregnancy Research 8 Centre, The Royal Women’s Hospital and 3 Department of Obstetrics and Gynaecology, 9 The University of Melbourne, Parkville 3052, Australia. 4 Murdoch Children’s Research 10 Institute and 5 Department of Clinical Haematology and 6 Department of Paediatrics, The 11 Royal Children’s Hospital and The University of Melbourne, Parkville 3052, Australia. 12 7 Graduate School of Biomedical Engineering, University of New South Wales, 13 Kensington 2033, Australia. 14 15 Corresponding author: 16 Dr. Amy Chui 17 NorthWest Academic Centre 18 The University of Melbourne and Sunshine Hospital 19 PO Box 294, 176 Furlong Road 20 St Albans 3021, Australia 21 Tel: +61 3 8395 8088 22 Fax: +61 3 8395 8258 23 Email: akl.chui83@gmail.com 24 25 26 27 28