Quantitative Profiling of Drug Associated Proteomic Alterations by Combined 2-Nitrobenzenesulfenyl Chloride (NBS) Isotope Labeling and 2DE/MS Identification (Supporting Information) Keli Ou, †,║,# Djohan Kesuma, †,# Kumaresan Ganesan, †,# Kun Yu, ‡ Sou Yen Soon, †, ║ Suet Ying Lee, † Xin Pei Goh, † Michelle Hooi, † Wei Chen, † Hiroyuki Jikuya, †,║ Tetsuo Ichikawa, †,║ Hiroki Kuyama, § Ei-ichi Matsuo, § Osamu Nishimura, § Patrick Tan *,†,‡,ℓ Agenica Research/National Cancer Centre/Genome Institute of Singapore, 11 Hospital Drive, Singapore 169610; Shimadzu (Asia Pacific), 16 Science Park Drive, Singapore 118227; Shimadzu Corporation, Kyoto, Japan 604-8511 * To whom correspondence should be addressed. Patrick Tan, National Cancer Centre, Singapore, Tel: (+65) 64368345. Fax: (+65) 62265694. Email: cmrtan@nccs.com.sg # These authors contributed equally to the project † Agenica Research ‡ National Cancer Centre of Singapore ℓ Genome Institute of Singapore ║ Shimadzu (Asia Pacific) Pte Ltd § Shimadzu Corporation (Kyoto, Japan) Running title: Quantitative Proteomics Using NBS/2DE/MS 1