www.ijbcp.com International Journal of Basic & Clinical Pharmacology | June 2017 | Vol 6 | Issue 6 Page 1367
IJBCP International Journal of Basic & Clinical Pharmacology
Print ISSN: 2319-2003 | Online ISSN: 2279-0780
Original Research Article
Effect of pharmacovigilance training programme on quantitative and
qualitative adverse drug reaction reporting
Sangita D. Jogdand
1
*, Mugdha R. Padhye
1
, Shailesh Nagpure
1
, Raju K. Shinde
2
INTRODUCTION
Vast numbers of the drugs are available in markets which
are widely prescribed by physician that leads to increased
number of adverse drug reactions (ADR). Newer drug
molecules are being constantly entering in the market that
needs to be monitored for its ADR. Monitoring of ADRs
related old as well as newer drug is essential because all
the drugs are usually tested in controlled conditions with
strict inclusion and exclusion criterion usually in
developed western countries that have different genetics
and environmental condition than that of Asian countries.
In real life situations after marketing, the drug is being
prescribed to all indicated patients in all age groups either
alone or with other drugs. Drug may be prescribed in
pregnancy unless contraindicated. Obscured ADRs or
unexpected therapeutic benefits may be discovered in
Pharmacovigilance studies. Mortality and high morbidity
due to ADR impose substantial financial burden nearly
100 million dollars in US per year.
1
Periodic evaluation of ADR helps to identify pattern of
ADR to improve the safety of the drugs. National and
International data helps in revision of labelling of product
and patients education program. Banning or withdrawal
of the drug after marketing is possible due to ADR
monitoring. Ideal Pharmacovigilance program should
have Monitoring, Detection, Evaluation, Documentation
and reporting of ADRs.
2
International adverse drug reaction monitoring centre is
managed by Uppsala Monitoring Centre at Sweden,
ABSTRACT
Background: Adverse Drug Reactions(ADRs) are required to monitored in
post marketing phase for unstudied ADR or beneficial effect which were not
evident in controlled study design, but ADRs are usually under reported due to
misbelieves or ignorance of health care worker. There is increasing numbers of
adverse drug reaction monitoring centers in India affiliated to governing council
but are in primitive phase. Also, there is lack of knowledge and attitude towards
necessity for proper reporting of ADR, understanding of terminologies. Hence
present study was undertaken to assess out of educational intervention in the
form of simulated ADR workshop.
Methods: Hundred nursing staff of JNMC were trained through Simulation
Workshop i.e. initial knowledge as assessed before intervention, followed by
explanations of every terminology essential for quality reporting of ADR. Ideal
ADR reports were provided for study and ADR scenario was given for reporting
of ADR. Deficiencies in reported ADR explained to participants. Post
intervention knowledge and reporting was assessed. Deficiencies in actual ADR
were pursued for three months.
Results: There was statistically significant improvement observed in
knowledge (p <0.01) and corresponding, proportionate quality parameters of
ADRs as suggested by Z test.
Conclusions: Educational intervention through simulated ADR and
understanding about significance of ADR reporting’s and related terminologies
improves quality as well as numbers of ADR reporting.
Keywords: Adverse drug reaction, Pharmacovigilance, Quality report
DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20172225
1
Department of Pharmacology,
2
Department of Surgery,
Jawaharlal Nehru Medical
College, Sawangi, Meghe,
Wardha, Maharashtra, India
Received: 16 March 2017
Accepted: 22 April 2017
*Correspondence to:
Dr. Sangita D. Jogdand,
Email: drsangitaraj@gamil.com
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