Data Descriptor: First draft genome sequence of the rock bream in the family Oplegnathidae Younhee Shin 1,2 , Myunghee Jung 1,3 , Ga-hee Shin 1 , Ho-jin Jung 1 , Su-Jin Baek 1 , Gi-Yong Lee 1 , Byeong-Chul Kang 1 , Jaeyoung Shim 1 , Ji-man Hong 1 , Jung Youn Park 4 , Cheul Min An 4 , Young-Ok Kim 4 , Jae Koo Noh 4 , Ju-Won Kim 4 , Bo-Hye Nam 4 & Chan-Il Park 5 The rock bream (Oplegnathus fasciatus) is one of the most economically valuable marine fish in East Asia, and due to various environmental factors, there is substantial revenue loss in the production sector. Therefore, knowledge of its genome is required to uncover the genetic factors and the solutions to these problems. In this study, we constructed the first draft genome of O. fasciatus as a reference for the family Oplegnathidae. The genome size is estimated to be 749 Mb, and it was assembled into 766 Mb by combining Illumina and PacBio sequences. A total of 24,053 transcripts (23,338 genes) are predicted, and among those transcripts, 23,362 (97%), are annotated with functional terms. Finally, the completeness of the genome assembly was assessed by CEGMA, which resulted in the complete mapping of 220 (88.7%) core genes in the genome. To the best of our knowledge, this is the first draft genome for the family Oplegnathidae. Design Type(s) sequence analysis objective • sequence assembly objective Measurement Type(s) whole genome sequencing Technology Type(s) DNA sequencing Factor Type(s) Sample Characteristic(s) Oplegnathus fasciatus 1 Research and Development Center, Insilicogen Inc., Yongin-si 16954, Gyeonggi-do, Republic of Korea. 2 Department of Biological Sciences, Sungkyunkwan University, Suwon, 16419, Republic of Korea. 3 Department of Forest Science, Research Institute of Agriculture and Life Science, College of Agriculture and Life Sciences, Seoul National University, Seoul, 08826, Republic of Korea. 4 Biotechnology Research Division, National Institute of Fisheries Science, Haean-ro 216, Gijang-eup, Gijang-gun, Busan, 46083, Republic of Korea. 5 Department of Marine Biology & Aquaculture, College of Marine Science, Gyeongsang National University, 455, Tongyeong, 53064, Republic of Korea. Correspondence and requests for materials should be addressed to B.-H.N. (email: nambohye@korea.kr) or C.-I.P. (email: vinus96@hanmail.net) OPEN Received: 19 December 2017 Accepted: 4 September 2018 Published: 23 October 2018 www.nature.com/scientificdata SCIENTIFIC DATA | 5:180234 | DOI: 10.1038/sdata.2018.234 1