Biol Med Case Rep 2018 Volume 2 Issue 3 3 http://www.alliedacademies.org/biology-and-medicine-case-report/ Case Report The classifcation of vascular lesions of the oral cavity is complex. To simplify, these lesions can be divided into two large groups: neoplasms (mostly benign) and vascular malformations. Laser treatment of oral vascular lesions seems to be an excellent device, and different wavelengths have been reported in the literature. The purpose of this work is to document a case of vascular lesion of the lip, developed in a few weeks in an adult patient successfully treated with a minimally invasive technique with the use of diode laser 810 nm. A young adult female patient was referred for a labial exophytic lesion that continued to grow despite previous topical therapies prescribed by dermatologists. The frst dermatologist diagnosed herpetic manifestation and the second diagnosed labial granuloma. The patient has been subjected to ultrasound examination, which confrmed the suspected diagnosis of the benign vascular injury. The patient underwent 3 photocoagulation sessions performed with 810 nm diode laser and after 2 months the lesion completely healed without scarring and without alteration of sensitivity. Lip diseases are often treated dermatologists, although the labial mucosa belongs to the oral cavity. Through the use of a safety device, this type of injury can be managed within the dental offce, and so an opportunity for dental practice. The diode laser can be considered safe and effective in the treatment of vascular lesions of the lip. Abstract Introduction The classifcation of vascular lesions of the oral cavity is complex and has recently changed. To simplify, these lesions can be divided into two large groups: neoplasms (mostly benign) and vascular malformations [1]. Hemangioma is a benign vascular lesion of the oral cavity and may also occur in the labial border [2]. Vascular malformations include a series of pathologies characterized by the alteration of vascular structures proliferation. These changes can be congenital or acquired, usually, the latter appear after a traumatic event or surgery [3]. They affect men more frequently and rarely affect the labial tissue. Diagnosis of these lesions is essentially clinical that are accompanied by instrumental investigations such as the eco color doppler. Although the use of a needle aspiration can help the clinician for an immediate diagnosis, avoid biopsies and subsequent analysis from microscopic histological images [4]. The biopsy is useful to other kinds of screening but it could cause copious bleeding [5]. Often it is possible to appreciate a pulsation of the blood vessels involved [3]. Another vascular entity affecting the lip is the persistent caliber artery. It’s an artery that infltrates even in submucous tissues and that doesn’t branch and isn’t reduced in size, causing the formation of labial lesions, which sometimes can undergo ulceration and therefore hemorrhage [6]. Also, in this case, clinical and ultrasound examination can lead us to the diagnosis without biopsies. Benign variants of vascular lesions that may affect the lip have been described in the literature, although very rare as angioleiomyoma and angiomyolipoma [7-9]. The treatment of this type of lesions is often required only for aesthetic reasons because are asymptomatic, especially if smaller than 1 cm and with a little risk of traumatization. Among the treatments proposed in the scientifc literature, there are sclerotherapy or injections with sodium tetradecyl sulfate [10,11], cryotherapy with liquid nitrogen [12], photocoagulation therapy with neodymium laser (1064 nm) and a high-intensity diode laser [13-15]. The purpose of this work is to document a case of vascular lesion of the lip, developed in a few weeks in an adult patient, successfully treated with a minimally invasive technique with the use of 808 nm diode laser. Clinical Case 29 years old female patient went to our private practice for a labial exophytic lesion. Anamnesis reported good general health condition and capillary fragility. She referred to us for some weeks, the lesion continued to grow despite previous topical therapies prescribed by dermatologists. A specialist diagnosed herpetic manifestation and therefore patient was treated with topical antiviral therapy without any beneft. A second dermatologist diagnosed labial granuloma and prescribed topical antibiotic therapy, while the lesion continued to grow. Clinical appearance was a red lesion, about 1.5 cm in diameter, which was lightened to pressure (Figure 1). It was decided to subject the patient to an ultrasound examination, which confrmed the suspected diagnosis of the benign vascular injury. Given the site and the protrusion of the lesion, so the traumatic risk with possible hemorrhage, it was decided to act conservatively. The patient underwent 3 photocoagulation sessions performed with 810 nm diode lasers, 2 weeks after each session. The Vascular lesion of the lip treated with a diode laser: A case report. Cinzia Casu 1 *, Riccardo Botta 2 , Carla Mannu 3 1 Private Dental Practice, Cagliari, Italy 2 Department of Dentistry, IRCSS San Raffaele Hospital, Vita Salute, Dental School, University of Milano, Milano, Italy 3 Diabetology, San Michele Hospital, Cagliari, Italy Accepted on November 28, 2018 Keywords: Lip lesions, Vascular oral lesion, 808 nm Diode laser, Vascular lip lesions.