* Corresponding author : E-mail: aymanelghamry@mans.edu.eg Authors' e-mails: 2 nouraalahmady@yahoo.com; 1 ahmedmosa@mans.edu.eg 3 aymanco@mans.edu.eg; 4 eselim2016@du.edu.eg; 5 haroun.aboushama@gebri.usc.edu.eg; 6 ahmedelsawah89@mans.edu.eg 7 hassan.elramady@agr.kfs.edu.eg; Received: 27/1/2021; Accepted: 22/2/2021 DOI: 10.21608/jenvbs.2021.60183.1128 ©2021 National Information and Documentation Center (NIDOC) T HE GENERATION of new elements inside living cells, either by nuclear fusion or nuclear fission is questionable. Nuclear fusion theory can interpret the increase of an element or reduction of another one following the dissociationof the atomic nucleus of some elements and recoordination of new integrated nuclei, which surrounded by electrons to neutralize protons of nucleus. To proof our hypothesis, in vitro microcosm investigations were carried out using two microbial stains (Bacillus amyloliquefaciens MN592674B and Escherichia coli), which spiked with seven trace elements (Ti, V, Co, Ni, Se, Mo, and B) in a closed system. Total trace element concentrations were determined using Inductivity Coupled Plasma Optical Emission Spectrometry (ICP-OES) at the end of inoculation experiment. Some trace elements (e.g. Se, V and Ni) showed increments, others (e.g. Ti and B) showed reductions; however, some trace elements such asAg, B and Cdvanished completely from the microbial media. The addition of V, Co, Ni, Se, Mo and B to B. amyloliquefaciens culture medium enhanced Bismuth (Bi) bioforming.This finding was also supported by Energy Eispersive X-ray Spectroscopy (EDS) data, which showed substantial alterations in metals distribution in the outersphere surfaces as affected by the microbial strain and the spiked elements. In this regard, trace elements transformation differed greatly among bacterial strains. Findings from this investigation provide insights for understanding elemental transformations in the living cells. Further studies are urgent and needed for more insights concerning this vital theme. Keywords: Bacillus amyloliquefaciens, Escherichia coli, Trace elements, Nuclear fusion. The Living Cells and Elemental Synthesis: New Insights Ayman M. El-Ghamry 1* , Noura El-Ahmady El-Naggar 2 , Ahmed A. Mosa 1 , Ayman Y. El-Khateeb 3 , El-Metwally M. Selim 4 , Haroun M. AboShama 5 , Ahmed M. El-Sawah 6 and Hassan El-Ramady 7 1 Soils Dept., Faculty of Agriculture, Mansoura University, 35516Mansoura, Egypt. 2 Department of Bioprocess Development, Genetic Engineering and Biotechnology Research Institute, City of Scientifc Research and Technological Applications (SRTA- City), Alexandria, 21934, Egypt. 3 Agricultural Chemistry Dept., Faculty of Agriculture, Mansoura University, 35516 Mansoura, Egypt. 4 Soils Dept., Faculty of Agriculture, Damietta University, 34517 Damietta, Egypt. 5 Plant Biotechnology Dept., Genetic Engineering and, Biotechnology Institute, Sadat City University, 32958 Sadat, Egypt. 6 Agricultural Microbiology Dept., Faculty of Agriculture, Mansoura University, 35516 Mansoura, Egypt. 7 Soil and Water Dept., Faculty of Agriculture, Kafrelsheikh Uni., 33516 Kafr El- Sheikh, Egypt. Env. Biodiv. Soil Security Vol. 5 pp. 41-57 (2021) Environment, Biodiversity & Soil Security (EBSS) http://jenvbs.journals.ekb.eg// 4