Jebmh.com Original Article J. Evid. Based Med. Healthc., pISSN- 2349-2562, eISSN- 2349-2570/ Vol. 3/Issue 14/Feb. 18, 2016 Page 507 PRE METABOLIC STATE - A NEW VARIANT TO BE INTRODUCED Shubham Gupta 1 , Samarth Shukla 2 , Sourya Acharya 3 1 Final Year Student, Department of Pathology, Jawaharlal Nehru Medical College. 2 Professor, Department of Pathology, Jawaharlal Nehru Medical College. 3 Professor, Department of Medicine, Jawaharlal Nehru Medical College. ABSTRACT BACKGROUND In this era of busy and stressful life, medical students rarely get time for their own health concerns. They lead sedentary life style with less physical activities and also have immense physical, mental, social and emotional stress which has detrimental effects on their health. These hard facts impose a negative effect on their metabolic health in specific relating to weight gains, altered lipid profiles, raised blood glucose levels and even stress induced elevated blood pressure. Keeping this context we proposed to study to coin a new terminology as pre- metabolic state. AIM To evaluate and coin a new term of pre-metabolic state in potentially obese candidates through assessment of their various metabolic parameters. OBJECTIVES To assess the biological/serological markers according to the NHANES (The National Health and Nutrition Examination Survey) guidelines for metabolic states and to correlate the clinical and physical findings in these medical graduates with their biochemical profiles. METHOD 120 medical students were assessed on the basis of a detailed history on a basis of a predesigned questionnaire attending Internal medicine OPD. Detailed anthropometric measurements and blood pressure was recorded. Blood glucose, lipid profile was estimated. STATISTICAL ANALYSIS Chi-Square test was applied and (p<0.005) was considered significant. RESULT Overweight subjects had increased prevalence of pre-hypertension and hypertension, impaired blood glucose level, decreased HDL and elevated triglyceride level. CONCLUSION A new terminology like “premetabolic state” may be proposed for overweight individuals who also have any one criteria of metabolic syndrome present in them. KEYWORDS Premetabolic state, Metabolic syndrome, Pre hypertension, Hypertension. HOW TO CITE THIS ARTICLE: Gupta S, Shukla S, Acharya S. Pre metabolic state - a new variant to be introduced. J. Evid. Based Med. Healthc. 2016; 3(14), 507-512. DOI: 10.18410/jebmh/2016/116 INTRODUCTION: The yin and yang between communicable and non-communicable diseases has been always there, however with change in life styles and major transitions in working trends and patterns amongst human beings has opened wide the door for emergence of an array of non-communicable diseases. The global trends of current times has shown a remarkable upsurge in cardiovascular and diabetes mellitus and their associated complications. [1] Presently various meta analytical works on international fronts points towards obesity as a major harbinger of propagating and accentuating cardiovascular diseases as well as Diabetes Mellitus. Indian as well as international studies on epidemiology suggest a rapidly rising trend in cardiovascular diseases especially in the last two decades. And by 2020 India will have a large proportion of population contributing to morbidity and mortality due to cardiovascular diseases. [2,3] The obesity patterns along with diabetes and cardiovascular Submission 20-01-2016, Peer Review 03-02-2016, Acceptance 15-02-2016, Published 18-02-2016. Corresponding Author: Dr. Samarth Shukla, Department of Pathology, Jawaharlal Nehru Medical College, Wardha, Maharashtra. E-mail: samarth21174@gmail.com DOI: 10.18410/jebmh/2016/116