Open Journal of Internal Medicine, 2016, 6, 43-55 Published Online June 2016 in SciRes. http://www.scirp.org/journal/ojim http://dx.doi.org/10.4236/ojim.2016.62009 How to cite this paper: Jani, Y., Xhunga, S., Serani, A., Pocesta, B., Ferati, F., Lala, D., Zeqiri, A. and Rexhepi, A. (2016) Ven- tricular Repolarization: Epidemiology and Clinical Correlates among Type-2 Diabetics with Uncontrolled Arterial Hyperten- sion in Western Region of the Republic of Macedonia. Open Journal of Internal Medicine, 6, 43-55. http://dx.doi.org/10.4236/ojim.2016.62009 Ventricular Repolarization: Epidemiology and Clinical Correlates among Type-2 Diabetics with Uncontrolled Arterial Hypertension in Western Region of the Republic of Macedonia Ylber Jani 1* , Sotiraq Xhunga 2 , Artur Serani 2 , Bekim Pocesta 3 , Fatmir Ferati 4 , Dali Lala 5 , Agim Zeqiri 6 , Atila Rexhepi 4 1 Private Health Institute, “Heart Diagnostica”, Debar, Republic of Macedonia 2 Department of Cardiology Medical Center, Dures, Republic of Albania 3 Department of Cardiology, Faculty of Medicine, “Ss Kiril and Metodij” University, Skopje, Republic of Macedonia 4 Department of Internal Medicine, Faculty of Medicine, Tetovo, Republic of Macedonia 5 Private Health Institute of Family Medicine “Florenc”, Tetovo, Republic of Macedonia 6 Department of Internal Medicine, General Hospital “DR Ferit Murat”, Gostivar, Republic of Macedonia Received 15 April 2016; accepted 18 June 2016; published 21 June 2016 Copyright © 2016 by authors and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/ Abstract This study aimed to describe the epidemiology of repolarization dispersion (QT dispersion and Tpeak-Tend dispersion) and further describe their associated clinical correlates among uncon- trolled arterial hypertension in type-2 Diabetics patient, in western region of the Republic of Ma- cedonia. Abnormal ventricular repolarization is associated with increased cardiovascular risk. Data relating to the frequency of increased repolarization dispersion, among uncontrolled arterial hypertension in type-2 Diabetics patient in western region of the Republic of Macedonia, are scarce. A total of 600 patients were enrolled into this observation study. Study participans were selected among primary care patient, who were receiving ongoing care for diabetes mellitus and hypertension during 1 calendar year. Twelve lead resting electrocardiography, QT, QTc, Tpeak- Tend-intervals and dispersions, were determined manually, and were compared between groups. Patients with uncontrolled BP have greater frequency of: prolonged QTc.max.interval, (61.3% vs.33.6%; p = 0.0005), prolonged Tpeak-Tend interval (65.3% vs. 34.7%; p = 0.005), increased dispersion of QTc. interval (65.9% vs. 34.1%; p = 0.00), increased disperion of Tpeak-Tend * Corresponding author.