being reported. A 32-year-old male presented with a 5.0-cm ulcerated lateral palatal swelling and a history of recently diagnosed HL. Clinical impression was palatal abscess, r/o HL. Diagnosis on biopsy was malignant lymphoid infiltrate, consistent with HL. The patient was determined to have stage IV HL, with involvement of the low pelvic area, oral cavity, and cervical lymph node chain. A second case of extranodal HL of the oral soft tissue was identified in a 70- year-old female as a swelling of the floor of the mouth. Clinical impression was mucocele, r/o salivary gland tumor. The biopsy specimen was diagnosed on routine microscopy as consistent with lymphocyte-predominant HL. The diagnosis was confirmed by immunohistochemical analysis. A diagnosis of stage I HL was made based on the absence of any detectable sites of involvement outside of the oral cavity. After treatment, the patient was considered free of disease at 6-month follow-up. These 2 cases contribute to the paucity of cases documented in the literature of extranodal HL of oral soft tissues. SOME PITFALLS OF MEDLINE SEARCHES USING KEYWORD AND MeSH PROTOCOLS. K. Summersgill, University of Pittsburgh, Pa. Background and objective. The use of computerized databases has revolutionized how we perform literature searches. However, some methods are more efficient and fruitful than others. This research was performed to identify some pitfalls of literature search protocols. Study design. Using the Medline database from 1996 to November 15, 2003, in the OVID interface, the author performed keyword and Medical Subject Heading (MeSH) searches of commonly misspelled words and words with different British and American spelling and containing diacritical marks such as umlauts and tildes. Results. In a keyword search, misspelled words or variants ‘‘boney,’’ ‘‘persistance,’’ ‘‘inflamation,’’ and ‘‘erythematosis’’ occurred 16, 51, 10, and 97 times, respectively, as compared to 5,682, 11,019, 52,227, and 7,434 times for the correctly spelled entries. In general, diacritical marks are ignored in keywords, authors’ names, and MeSH headings. The American form of a keyword greatly predominated over the British spelling of a keyword, and was much more likely to map more specifically to MeSH headings. Those entries with a misspelled word often also contained the correctly spelled version. The use of MeSH headings usually yielded more specific results than the use of keywords. Conclusion. Although using keywords in literature searches is sometimes easier than using MeSH, one is likely to miss numerous relevant citations. In performing Medline database searches, we must be aware of the particular quirks of spelling and usage of the program. SUBMUCOSAL CALCIFIED NODULE OF THE LOWER LIP: REPORT OF A CASE. D. Antoniades, A. Markopoulos, Aristotle University, Thessaloniki, Greece. Background. The subepidermal calcified nodule is a form of idiopathic calcinosis cutis that affects children and is occasionally present at birth. The most common locations are the extremities and the face. The oral and perioral regions are very rarely affected by calcinosis cutis of any type. Case report. A 1-year-old white girl was referred to the Department of Oral Medicine and Maxillofacial Pathology of the School of Dentistry, Aristotle University, Thessaloniki, Greece, for evaluation of a white hard nodular lesion that had been present on her lower lip since birth. The patient had no history of connective tissue disease or calcium and phosphorus abnormalities. The nodule was surgically excised and was histopathologically and immunohisto- chemically examined. The sections stained with H&E revealed a cystic lesion filled with calcified material. A thin layer of inflammatory and epithelioid cells was arranged around the calcium deposits. Immunohistochemically these cells were CD68-positive and negative to keratins. These findings were compatible with a diagnosis of submucosal calcified nodule. Conclusion. The subepidermal calcified nodule is characterized by the presence of calcified material which is usually located in the uppermost lamina propria. The calcium is present as irregular granules and globules. The exact mechanism that leads to excessive calcification is not clear. MUCUS RETENTION CYST WITH DEVELOPMENT OF BASAL CELL ADENOMA: REPORT OF A CASE. D. Antoniades, A. Markopoulos, T. Zaraboukas, A. Epivatia- nos, Aristotle University, Thessaloniki, Greece. Background. Mucus retention cyst is a relatively uncommon lesion of the salivary gland. Unlike the more common mucus escape reaction, it is a true cyst that is lined by epithelium consisting of a uniform layer of cuboidal to low-columnar cells. However, a uniform thin layer of nonkeratinizing stratified squamous epithelium is common, and occasional mucous cells within the epithelial lining of the cyst can be observed. Some authors have mentioned that in some cases the epithelium demonstrates papillary folds into the cystic lumen, when these lesions are misdiagnosed as papillary cystadenoma. Other authors contend that mucus retention cysts do not show piling up of cells in the wall of the cyst and neither proliferation nor infiltration of islands of epithelium into the connective tissue is a feature. These histologic features with connection to the absence of multicystic structures and of areas of solid epithelial proliferations are particularly important to rule out cystic neoplasms. Also, in the literature review, we could not find any reported case of mucus retention cyst with development of a neoplasm from the lining epithelium. Case report. A 68-year-old man was referred to the Department of Oral Medicine and Oral Pathology of the Aristotle University Dental School, Thessaloniki, Greece, because of a painless swelling that periodically fluctuated in size. Intraoral examination revealed a well demarcated mass, soft to palpation, measuring 1.5 3 1cm, located in the submucosa of the upper lip. The covered mucosa was reddish-blue in color. Under local anesthesia the lesion was totally excised. Histologic examination showed the presence of a monocystic lesion lined by atrophic epithelium in proximity to normal minor salivary glands. Islands consisting of single layered cuboidal or columnar epithelial cells were also observed in contact with the lining epithelium and floating into the cystic cavity. These cell islands, when examined immunohistochemically, reacted positively in keratin 7 and S-100 protein and negatively for vimentin. Conclusion. The histologic and immunohistochemical findings supported diagnosis of mucus retention cyst with development of basal cell adenoma. Differential diagnosis of the tumor is discussed. CLINICOPATHOLOGIC STUDY OF 174 EPULI IN DOGS. C. Felizzola, N. Arau ´jo, V. Arau ´jo, D. Pinto Jr., S. Sousa, University of Sa ˜o Paulo School of Dentistry, Brazil. Epulis is a clinical term that has longed been used to diagnose gingival lesions occurring in dogs. Attempts have been done to individualize these lesions, and classifications have been proposed, some of which attempt to correlate dog lesions to those occurring in humans. Studies have shown that although some resemblance does exist, the lesions tend to be different in histologic aspects and clinical OOOOE 208 Abstracts August 2004