Original Article The Relationship between Demographic Factors in Adult Patients with Stroke Samad Shams-Vahdati 1 , Alireza Ala 1 , Eliar Sadeghi-Hokmabad 2 , Neda Parnianfard 3 , Nasim Ahmadi Sepehri 2 *, Maedeh Gheybi 2 1 Emergency Medicine Department, Imam Reza Hospital, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran 2 Neurology department, neuroscience research center, Tabriz University of Medical Sciences, Tabriz, Iran 3 Research Center for Evidence-Based Medicine, Health Management and Safety Promotion Research Institute, Iranian EBM Center: A Joanna Briggs Institute Affliated Group, Tabriz University of Medical Sciences, Tabriz, Iran Corresponding Author: Nasim Ahmadi Sepehri, E-mail: nasimsepehr@ymail.com ABSTRACT Background: Developing countries are challenging with stroke as the third cause of death in developed countries and the most popular neurologic disease which results in disability. This study was designed to assess the relationship between demographic factors and early outcome in adult patients with difference type of stroke. Methods and Materials: A retrospective register review was performed from March 2017 to March 2018. ED medical document (chart) were reviewed by a neurologist or physician to obtain the clinical diagnosis, patient characteristics. Their demographic data (such as age, gender), NIHSS score and MRS score were flled in questionnaire. the signifcant variables were verifed in a multivariable model to achieve an attuned estimate of effect. Results: A total of 861 patients with stroke were included in the analysis; the male and female sex in the statistical population were 56% and 43%; the mean age of the patients was 14.32 ± 61.74. The mean NIHSS (16.08±10.51) & MRS (3.66) scores were evaluated, respectively 47% severe stroke (NICHSS>16). There was no signifcant relationship between age increase and NIHSS increase (P = 0.86). Conclusion: Aging has a signifcant relationship with increased stroke. Gender and age differences in risk of stroke outcomes are mostly described by variations in physical characteristics and stroke severity of the patients. BACKGROUND Stroke is an unavoidable condition of increasing social and economic prominence in healthy populations. In relation to the World Health Organization, stroke is ranked as the sec- ond cause of death globally in 1990 and it is the third leading reason of death in developed countries (1); it accounts for 4.4 million deaths worldwide (2). Stroke is not only a death cause, it also the main cause for long-term inabilities and heavy burden in terms of emotional, social, and econom- ic costs for patients, their families and healthcare services. The cost of longevity of each patient is estimated between $59,800 and $230,000. Stroke and coronary artery disease are predicted to be the main cause of healthy years of life in 2020 (3). The effects of improved onset and survival chang- es on the reduction in mortality due to strokes have not been adequately measured, which is mainly due to problems with truthful dimension of the stroke prevalence. Data from the stroke project of WHO (MONICA) examined the gener- al trend of fatality and stroke in people with age range of 35-64. The age of stroke is older in males than in females. Nevertheless, a lengthier life expectation for females and a sharp rise in stroke at aging will increase the number of women with stroke (2-5). Although studies generally sug- Published by Australian International Academic Centre PTY.LTD. Copyright (c) the author(s). This is an open access article under CC BY license (https://creativecommons.org/licenses/by/4.0/) http://dx.doi.org/10.7575/aiac.abcmed.v.7n.4p.14 gest evidence of worsening outcomes in women, the recent study suggests several studies of which men are based poor results and many studies with parallel results for males and females (5). Meanwhile there are sex and age variances in the physical characteristics of patients. We examined the gender and age variances in patients’ characteristics in ad- mittance and organization, and results in subtype of stroke. METHOD AND MATERIAL A retrospective medical records assessment was completed on all patients with a fnal diagnosis of stroke during a period from March 2017 to March 2018. Patient who referred to the emergency department (ED) of Imam Reza hospital then admitted to neurology department. This hospital is a certifed stroke center, and comprehends more than 1000 stroke codes in the ED each year. Patients were included in this study who aged more than 14 years and admitted to the neurology de- partment. Patients exposed to transient clinical ischemic at- tacks without imaging correlation were excluded from the study. The fndings of the imaging have been confrmed by the radiologist. All patients were examined by a neurologist. Demographic data and medications were recorded at the be- Advances in Bioscience and Clinical Medicine ISSN: 2203-1413 www.abcmed.aiac.org.au ARTICLE INFO Article history Received: July 12, 2019 Accepted: September 21, 2019 Published: October 31, 2019 Volume: 7 Issue: 4 Conficts of interest: None Funding: None Key words: Gender, Age, Stroke