Accepted Manuscript 1 © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com. Sepsis-like disease in infants due to Human Parechovirus-3 during an Outbreak in Australia Khatami A. 1 , McMullan B.J. 2 , Webber M. 3 , Stewart P. 1 , Francis S. 2 , Timmers K.J. 3 , Rodas E. 4 , Druce J. 5 , Mehta B. 1 , Sloggett N.A. 1 , Cumming G. 6 , Papadakis G. 5 and Kesson A.M. 1,7 1 The Children’s Hospital at Westmead, Sydney, NSW, Australia 2 Sydney Children’s Hospital, Sydney, NSW, Australia 3 The John Hunter Children’s Hospital, Newcastle, NSW, Australia 4 Wollongong Hospital, NSW, Australia 5 The Victorian Infectious Diseases Reference Laboratory, Melbourne, VIC, Australia 6 NSW Ministry of Health, Public Health Officer Training Program, Sydney, NSW, Australia 7 Discipline of Paediatrics and Child Health, and Marie Bashir Institute for Emerging Infectious Diseases and Biosecurity, University of Sydney, NSW, Australia Corresponding Author: Ameneh Khatami, Fellow in Infectious Diseases and Microbiology, The Children’s Hospital at Westmead, Hawkesbury Road, Westmead, NSW 2145, Australia, Email: ameneh.khatami@health.nsw.gov.au, ameneh.khatami@gmail.com, Telephone: +61 2 98453274, Fax: +61 2 98453291 Alternative Author: Brendan McMullan, Staff Specialist in Infectious Diseases, Sydney Children’s Hospital, High St, Randwick, NSW 2031, Australia, Email: Brendan.McMullan@sesiahs.health.nsw.gov.au, Telephone: +61 2 9382 1508, Fax: +61 2 9382 1580 Main points: We describe the clinical presentations of 118 infants admitted to hospital in New South Wales, Australia during an epidemic of human parechovirus-3. Infants presented with an acute sepsis-like syndrome with a high rate of intensive care admission. Clinical Infectious Diseases Advance Access published October 9, 2014 by guest on December 2, 2015 http://cid.oxfordjournals.org/ Downloaded from