Nightmares share strong genetic risk with sleep and psychiatric disorders Hanna M Ollila†1,2,3,4, Nasa Sinnott-Armstrong*4, Katri Kantojärvi*5,6, Teemu Palviainen1, Anita Pandit7, Robin Rong7, Kati Kristiansson5, Nils Sandman8, Katja Valli8,9, Christer Hublin10,11, Jaakko Kaprio1,11, Richa Saxena†3,12,13, Tiina Paunio†5,6 1. Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland. 2. Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA., USA. 3. Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA., USA and Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA. 4. Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA. 5. Genomics and Biomarkers Unit, Finnish Institute for Health and Welfare, Helsinki, Finland. 6. Department of Psychiatry and SleepWell Research Program, Faculty of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland. 7. Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA. 8. Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center, University of Turku, Turku, Finland. 9. Department of Cognitive Neuroscience and Philosophy, University of Skövde, Skövde, Sweden. 10. Finnish Institute of Occupational Health, Helsinki, Finland. 11. Department of Public Health, University of Helsinki, Helsinki, Finland. 12. Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. 13. Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. * Equal contribution † Correspondence Correspondence should be addressed to Professor Tiina Paunio Tiina.paunio@thl.fi Genomics and Biomarkers Unit, Finnish Institute for Health and Welfare, Helsinki, Finland And to Richa Saxena rsaxena@broadinstitute.org;Hanna M. Ollila hanna.m.ollila@helsinki.fi . CC-BY 4.0 International license not certified by peer review) is the author/funder. It is made available under a The copyright holder for this preprint (which was this version posted November 9, 2019. . https://doi.org/10.1101/836452 doi: bioRxiv preprint