Revascularization of the Occluded
Right Coronary Artery During Left
Ventricular Assist
Device Implantation
Evgenij V. Potapov, MD,
a
Ralf Sodian, MD,
a
Matthias Loebe, MD, PhD,
c
Thorsten Drews, MD,
a
Stephan Dreysse, MD,
b
and
Roland Hetzer, MD, PhD
a
A 62-year-old man with end-stage ischemic cardiomyopathy and left ventricular
function of 20% was evaluated for heart transplantation. Cardiac catheterization
revealed proximal occlusion of the dominant right coronary artery (RCA) with
collateral blood flow and significant stenosis in the distal part, but no significant re-
occlusions of the stented left coronary artery and no significant stenosis of the left
circumflex artery. When the patient became catecholamine dependent, Novacor left
ventricular assist device (LVAD) implantation, as a bridge to transplantation, was
considered and the patient operated upon. To avoid ischemic right heart failure
after LVAD implantation, a concomitant re-vascularization of the distal RCA was
performed. The post-operative course was uneventful. Five weeks later, a control
angiogram showed the patent bypass graft. The distal stenosis of the RCA was
treated successfully with dilation and stent implantation. The patient is presently in
stable condition on LVAD and awaits transplantation as an outpatient. J Heart
Lung Transplant 2001;20:918–922.
Right heart failure is a most feared complica-
tion after left ventricular assist device (LVAD)
implantation, with a reported incidence of be-
tween 20% and 52%.
1,2
As possible origins, a
change in the right ventricular geometry and
interaction,
2,3
increased right ventricular preload,
3
decreased contractility
3
and ischemia
4,5
have been
postulated. Its prevention is limited to careful
selection of patients with preserved right heart
function, which is pre-operatively difficult to esti-
mate,
6
and treatment by post-operative use of
inhaled nitric oxide,
7
careful volume substitution
and use of catecholamines to maintain optimal
organ perfusion without right heart overload.
7
One case of emergency right coronary revascular-
ization
4
and as ultima ratio an RVAD implanta-
tion
1
have been reported. The most important
factor in preserving adequate right heart function
is minimizing intraoperative damage to the right
ventricle, particularly ischemia caused by malper-
fusion, air embolism or volume overload.
We report a patient scheduled for Novacor
LVAD implantation with high risk for right heart
failure. In this case, preventive steps were taken
during and after surgery (performed by M.L.) and
led to an uneventful post-operative course.
CASE REPORT
A 62-year-old man with end-stage ischemic
cardiomyopathy was admitted to our unit in evolv-
ing cardiogenic shock despite optimal medical
treatment, including diuretics, digitalis, nitroglyc-
From the
a
Department of Cardiothoracic and Vascular Surgery,
b
Department of Cardiology, Deutsches Herzzentrum Berlin,
Berlin, Germany; and
c
Michael E. DeBakey Department of
Surgery, Division of Transplantation and Assist Devices, Bay-
lor College of Medicine, Houston, Texas.
Submitted November 10, 2000; accepted January 25, 2001.
Reprint requests: Evgenij V. Potapov, MD, Deutsches Herz-
zentrum Berlin, Augustenburger Platz 1, 13353 Berlin,
Germany. Telephone: +49-30-4593-1000. Fax: +49-30-
4593-2100. E-mail: potapov@dhzb.de.
Copyright © 2001 by the International Society for Heart and
Lung Transplantation.
1053-2498/01/$–see front matter PII S1053-2498(01)00266-2
918