CORRESPONDENCE
Exclusion of Mitral Valvuloplasty From Predictors of
Mortality for Patients Undergoing Cardiac Valve
Replacements in New York State
To the Editor:
We read with great interest the recent article by Hannan and
associates [1], which represented studies at an academic medical
center in New York State with an extremely large experience
with valvular heart surgery. Although the model created for
predicting mortality in valvular surgery was validated, we were
concerned by the incomplete treatment of mitral valve recon-
struction in this report. In their analysis the authors create
logistic regression models for all major groups of cardiac valve
operations with the exception of isolated mitral valvuloplasty.
Indeed, even within the isolated mitral replacement model the
effect of various valve types is independently tested. Meanwhile,
in Table 1 of their article, the authors separately identify 742
cases of mitral valvuloplasty that are not included in the logistic
modeling, while performing such a logistic analysis on the fewer
than 600 patients with mitral valve replacement and/or valvulo-
plasty and concomitant coronary artery bypass grafting. Assum-
ing that the mitral valvuloplasty category in Table 1 refers to
isolated mitral reconstruction, the crude mortality of 2.56%
makes the unadjusted mortality for mitral replacement 2.4-fold
that of mitral valvuloplasty. It is, therefore, very unclear as to
why no analysis was performed to test the effect of mitral
valuloplasty compared with mitral valve replacement, as it
seems intuitive that risk-adjusted modeling of such large patient
groups would be very instructive in determining whether there
is an independent hospital survival benefit from mitral valvulo-
plasty. Similarly, excluding these patients from the analysis may
skew the results significantly or perhaps even invalidate the
results of predictive mortality risk in all patients requiring
isolated mitral valve surgery.
In summary, we congratulate the authors on an excellent
analysis on predictors of mortality after valvular surgery, but
strongly suggest that they include mitral valvuloplasty patients
in any future analysis. The relevant data are readily available,
and inclusion of these patients would enhance the validity of
their results and strengthen any conclusions that are ultimately
based on their data.
Stephen B. Colvin, MD
Aubrey C. Galloway, MD
Eugene A. Grossi, MD
Department of Surgery
New York University School of Medicine
530 First Ave, Suite 9V
New York, NY 10016
Reference
1. Hannan EL, Racz MJ, Jones RH, Gold JP, Ryan TJ, Hafner J-P,
Isom OW. Predictors of mortality for patients undergoing
cardiac valve replacements in New York State. Ann Thorac
Surg 2000;70:1212– 8.
Reply
To the Editor:
The authors of our manuscript [1] sincerely appreciate the
comments of Colvin and associates and their many contribu-
tions to the field of valvular heart disease.
The analysis presented in the manuscript under discussion
was modeled on the STS National Database reports with regard
to choosing valve procedures for presentation. Although inde-
pendent risk factors were identified for mitral valve repair
during our analyses, they were not reported for this reason.
However, even if mitral valve repairs had been reported, the
direct comparison of mitral valve replacement and mitral valve
repair outcomes is problematic. The patient populations differ
significantly, and therefore the significant risk factors and out-
comes differ as well.
The authors’ suggestions for future investigation are appreci-
ated, and we agree with them that mitral valve repair is a
sufficiently important part of the modern surgical armentarium
to be considered for inclusion in future valve surgery reports.
Jeffrey P. Gold, MD
Edward L. Hannan, PhD
Michael J. Racz, MA
Robert H. Jones, MD
Thomas J. Ryan, MD
Jean-Paul Hafner, MD
O. Wayne Isom, MD
Department of Cardiothoracic Surgery
Montefiore Medical Center
Albert Einstein School of Medicine
111 E 210th St
Bronx, NY 10467
e-mail: elh03@health.state.ny.us.
Reference
1. Hannan EL, Racz MJ, Jones RH, Gold JP, Ryan TJ, Hafner J-P,
Isom OW. Predictors of mortality for patients undergoing
cardiac valve replacements in New York State. Ann Thorac
Surg 2000;70:1212– 8.
Combined Transseptal Superior Approach to Mitral
Valve: Management of Left Superior Vena Cava
To the Editor:
Of the various approaches for mitral valve operations, we have
been using the combined transseptal and superior approach
more often, and it is the approach of choice during minimally
invasive mitral valve operation as described by Cosgrove and
Gillinov [1]. The indications and efficacy of this approach have
been described previously [2, 3]. A persistent left superior vena
Fig 1. Direct left superior vena cava (LSVC) cannulation does not
interfere with exposure of the mitral valve.
© 2001 by The Society of Thoracic Surgeons Ann Thorac Surg 2001;72:663–9 • 0003-4975/01/$20.00
Published by Elsevier Science Inc PII S0003-4975(01)02754-0