Journal of Cancer Therapy, 2014, 5, 1000-1004 Published Online September 2014 in SciRes. http://www.scirp.org/journal/jct http://dx.doi.org/10.4236/jct.2014.511104 How to cite this paper: Amaadour, L., Benbrahim, Z., Benhayoune, K., Chbani, L., Arifi, S. and Mellas, N. (2014) Sporadic Desmoid Tumor of the Small Bowel Mesentery in a Male Patient: A Case Report and Literature Review. Journal of Cancer Therapy, 5, 1000-1004. http://dx.doi.org/10.4236/jct.2014.511104 Sporadic Desmoid Tumor of the Small Bowel Mesentery in a Male Patient: A Case Report and Literature Review Lamiae Amaadour 1* , Zineb Benbrahim 1 , Khadija Benhayoune 2 , Layla Chbani 2 , Samia Arifi 1 , Nawfel Mellas 1 1 Department of Medical Oncology, Hassan II University Hospital, Fez, Morocco 2 Department of Pathology, Hassan II University Hospital, Fez, Morocco Email: * lamiae.amaadour@gmail.com Received 20 July 2014; revised 18 August 2014; accepted 12 September 2014 Copyright © 2014 by authors and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/ Abstract Aggressive fibromatosis arising from the small bowel mesentery is extremely rare. It may occur in association with previous trauma, abdominal surgery, drugs, Gardner’s syndrome, or familial ade- nomatous polyposis. This paper presents a 32-year-old man with no significant medical or surgical history, complaining of diffuse abdominal pain and discomfort. His computed tomography scan revealed a well-defined soft tissue mass in the peritoneal cavity. He underwent surgical excision of the mass with resection and anastomosis of the involved loop of the small intestine. Histological examination confirmed mesenteric fibromatosis without infiltration of the bowel. The patient re- mained well during the 8 months follow-up. Keywords Desmoid Tumor, Mesenteric Fibromatosis, Surgery 1. Introduction Desmoid tumors (DT) are rare benign, monoclonal, myofibroblastic proliferations that originate from muscu- loaponeurotic structures. They are slow-growing and locally aggressive tumors with strong tendency to recur after surgical resection, but lack the capacity to metastasize. Mesenteric DT, also known as mesenteric fibroma- tosis, is a part of the clinical-pathologic spectrum of deep DT and represents the most common primary mesenteric neoplasm. * Corresponding author.