_____________________________________________________________________________________________________ *Corresponding author: E-mail: younismunshi@gmail.com; Journal of Complementary and Alternative Medical Research 16(4): 30-34, 2021; Article no.JOCAMR.73816 ISSN: 2456-6276 Role of Jundi-Shapur in Streamlining of ILM-E-TIBB (Medicine) Younis I. Munshi 1* and Masihuzzaman Ansari 1 1 Regional Research Institute of Unani Medicine, Kolkata, (CCRUM, Ministry of AYUSH, Govt. of India), India. Authors’ contributions This work was carried out in collaboration between both authors. Both authors read and approved the final manuscript. Article Information DOI: 10.9734/JOCAMR/2021/v16i430295 Editor(s): (1) Dr. Sahdeo Prasad, Texas Tech University Health Sciences Center, USA. (2) Dr. Francisco Cruz-Sosa, Metropolitan Autonomous University, México. Reviewers: (1) Anantkumar Shekokar, S.V.N.H.T Ayurved College, India. (2) Ashutosh Chauhan, Uttarakhand Ayurved University, India. (3) Kirti Rajendra Bhati, Deemed to be University, India. Complete Peer review History: https://www.sdiarticle4.com/review-history/73816 Received 20 July 2021 Accepted 29 September 2021 Published 09 October 2021 ABSTRACT People have always felt the need to seek the knowledge from time immemorial. Be it the knowledge of religion or science or philosophy or astronomy. The knowledge of medicine was confined to cultures till 4 th century AD. Every subcontinent and every civilization was having its own traditions to treat the diseases, e.g. Ayurved in India, Egyptian traditional medicine in Egypt, Chinese traditional medicine in China, Iranian Traditional medicine in Iran etc etc. It was during the 5 th century AD when Roman Empire cracked down on its seminaries and the intellectuals were forced to leave the country. Those intellectuals were given refuge by Persian Empire where in a city was established with ultimate autonomy under Khusro, Jundi-Shapur became a prosperous metropolis, refuge, and melting pot for intellectuals from many regions. Shapur II (309-379 A.D.) is credited for conceiving and establishing the nucleus of the university in the latter part of the fourth century. The closing of the Athenian school by the Byzantine Emperor Justinian (AD 539) also drove many leaned Greek physicians to Jundi-Shapur. This was the start of the integration of different traditional medicine of different civilizations. This formed the basis of what we see today as modern medicine. In this way JundiShapur has important role in the development of Medical knowledge and it remained in the leading role until 9 th Century AD. Review Article