Journal of Educational Sciences. Vol. 2, No. 1, 2018, 46-55 46 Received 4 th Dec 2017, Revised 15 th Jan 2018, Accepted for publication 16 th Jan 2018 Published by FKIP University of Riau Publisher, ISSN: 2581-1657 (Print), 2581-2203 (Online). Development of interactive multimedia based on Lectora Inspire in chemistry subject in junior high school or madrasah tsanawiyah Herdini Roza Linda, Abdullah, Nur Shafiani, Fitri ‘Alaina Darmizah, Praslita Dishadewi Program Studi Pendidikan Kimia, FKIP, Universitas Riau Pekanbaru, 28293, Indonesia Email: rozalinda@gmail.com Abstract. The research aims to develop interactive multimedia based Lectora Inspire on science chemistry subjects for SMP/MTs. The research method using the design of research and development (Research and Development) with a model Plomp, which consists of four phases; initial investigation, design, realization and construction, and validation, test and revision. The research was conducted at the University of Riau FKIP. The object of research is interactive multimedia Lectora Inspire. Data collected by validating based interactive multimedia Lectora Inspire to 3 validator (media expert and subject matter experts) and limited trial by users that teachers and students in SMP 4 and SMP Babussalam Pekanbaru. The results showed an average score of validator 98.20% . Score of limited trial based on questionnaire responses of teachers and students each obtained an average score of 98.78% and 97.03%. From the result of the average score of the validation and limited trial of interactive multimedia based Lectora Inspire for chemistry subjects for SMP / MTs valid and can be used as a learning media. Keywords: Lectora Inspire, interactive multimedia, the science chemistry subjects. 1 Introduction The development of Knowledge and Technology in the era of globalization is growing rapidly. This has an impact on various aspects of human life, including in education. Education is a major milestone in increasing human resources. In the field of education, especially in the learning process should be encouraged the growth of positive attitudes in the students themselves (Amri, 2013). The implementation of the mandate of Law No. 20 of 2003 is the implementation of the learning process that takes place in formal institutions, such as Junior High School (JHS)/MTs. One of the subjects studied by junior high school/MTs students is science subjects. Learning of Science (IPA) at the junior high school / MTs in the