International Journal of Research in Dermatology | March-April 2020 | Vol 6 | Issue 2 Page 132 International Journal of Research in Dermatology Choudhary A et al. Int J Res Dermatol. 2020 Mar;6(2):132-137 http://www.ijord.com Original Research Article Clinical evaluation of pathological dermatoses induced in pregnancy Anshul Choudhary, Kshitij Saxena*, Venket Rao Koti, Amir Shahid Ansari, Shivani Yadav, Titiksha Hans INTRODUCTION Pregnancyis characterized by endocrinal, metabolic and immunologic alterations which make the woman vulnerable to specific dermatoses, or a change in the course of coexisting skin diseases. 1 Specific dermatoses, Itching, skin infections, autoimmune skin diseases, skin tumors and inflammatory skin disorders may occur in pregnancy. Specific dermatoses of pregnancy are polymorphic eruption of pregnancy (PEP), pemphigoid gestationosis (PG), atopic eruption of pregnancy (AEP) and intrahepatic cholestasis of pregnancy (IHCP). These dermatoses are marked by severe pruritus and skin eruptions. IHCP is a reversible form of hormonally triggered cholestasis that typically develops in genetically predisposed individuals in late pregnancy. Reduced cell‐ mediated immunity during normal pregnancy probably accounts for the increased frequency and severity of certain infections such as candidiasis, herpes simplex and varicella zoster. Candida infection, genital warts and herpes simplex virus (HSV) can all be transmitted to the baby during childbirth. Pruritus gravidarum (itching in pregnancy) occurs in up to one‐fifth of all pregnancies. 2 The objectives of the study to identify and classify dermatoses occurring during pregnancy and to determine the prevalence of various dermatoses of pregnancy. Dermatoses during pregnancy can increase morbidity and mortality in the mother and the newborn. A knowledge of the profile of dermatoses during pregnancy is essential to plan preventive measures, care of the mother and the ABSTRACT Background: Pregnancy can present with various dermatoses which is divided into physiological and pathological dermatoses. These dermatoses have various effects on pregnancy and patient’s life. The objective was to study the various pathological dermatoses. Methods: A total of 1425 pregnant females attending dermatology, obstetrics and gynaecology Out Patient Department of Era’s Lucknow Medical College and Hospital were included, out of this 275 presented with pathological dermatoses. Detailed history, examination and investigations were done. Data was analysed using Statistical Package for Social Sciences version 21.0 (test). Results: Pathological dermatoses was seen in 275 pregnant females ranged between 18 to 45 years. Infections or infestations and STDs (53.5%) were the most common dermatological conditions followed by pregnancy specific dermatoses (24.7%), acne and folliculitis (7.6%), non-specific itching (5.8%) and other conditions (10.9%). Conclusions: Pregnant females suffer from number of pregnancy dermatoses. A knowledge of the profile of dermatoses during pregnancy is essential to plan preventive measures, care of the mother and the child. Keywords: Pregnancy, Pregnancy specific dermatoses, Infections, Pruritus Department of Dermatology, Era's Lucknow Medical College and Hospital, Lucknow, Uttar Pradesh, India Received: 12 January 2020 Revised: 28 January 2020 Accepted: 29 January 2020 *Correspondence: Dr. Kshitij Saxena, E-mail: drkshitijsaxena@live.com Copyright: © the author(s), publisher and licensee Medip Academy. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. DOI: http://dx.doi.org/10.18203/issn.2455-4529.IntJResDermatol20200506