http://www.revistadechimie.ro REV.CHIM.(Bucharest)♦69♦No. 10 ♦2018 2826 The Role of Saline Aerosols in the Prevention and Therapy of Cardio-respiratory and Osteo-muscular Afflictions IOAN GABRIEL SANDU 1,2 , VIORICA VASILACHE 3 , ANDREI VICTOR SANDU 1,2 *, MARIN CHIRAZI 4 , CEZAR HONCERIU 4 *, RADU CRISAN DABIJA 5 , ALINA VLADESCU 6 , COSMIN MIHAI COTRUT 7 , ION SANDU 2,3 * 1 Gheorghe Asachi Technical University of Iasi, Faculty of Material Sciences and Engineering, 69 Dumitru Mangeron Str.,700050, Iasi, Romania 2 Romanian Inventors Forum, 3 Sf. Petru Movila Str., 700089 Iasi, Romania 3 Alexandru Ioan Cuza University of Iasi, Interdisciplinary Research Department - Field Science, 54 Lascar Catargi Str., 700107 , Iasi, Romania 4 Alexandru Ioan Cuza University of Iasi, Faculty of Physical Education and Sport, 3 Toma Cozma Str., 700554, Iasi, Romania 5 Grigore T. Popa University of Medicine and Pharmacy, 16 Universitatii Str., 700115, Iasi, Romania 6 National Institute R&D for Optoelectronics - INOE 2000, 409 Atomistilor Str., 077125, Magurele, Ilfov, Romania 7 University Politehnica of Bucharest, Faculty of Material Science and Engineering, 313, Splaiul Independenei, Building J, 060042, Bucharest, Romania The saline aerosols generated in gaseous media, as nanodispersions, behave, with respect to the concentration levels and the lifespan, as trimodal distributions (the three domains with Gaussian distributions: fine or Aitken under 50 ìm, medium between 50 and 500 μm and, respectively, coarse or large between 500 and 1000 μm). The generation in latent state is dependent on the active surface of the source (number of generator centres, the size and position of the fluorescences, the porosity, size and shape of the source, etc.), the climatic parameters, but also on a series of other characteristics of the gaseous medium. Our team has demonstrated experimentally that saline aerosols, NaCl type, besides the ability to prevent and treat broncho-respiratory and cardiac conditions, through coassistance of saline aerosols of other cations than sodium, and of the iodine anion, have for certain levels of concentrations propitious effects over the immune, bone and muscular systems. Similarly proved has been the positive influence on the development of children, as well the determinant role in increasing athletic performance and of other human subjects performing intense activities. Keywords: solion, halochamber, microclimatic parameters, biometric characteristics, cardio-respiratory and osteo-muscular systems The obtaining, characterization and behaviour of saline aerosols has been addressed by our team for the last 18 years, under the influence of the results obtained in identifying a number of evolutionary markers of the salt rocks and brine from old wells (shafts) from the Moldavian piedmont area east of the Eastern Carpathians, Romania. The Subcarpathian area of Moldavia houses over 200 salt springs, with a notable role in the development of the human habitat [1-3]. The importance of the salt and of the salt springs was first underlined in the 1950s by the geographer Ion ‘andru and chemist Petru Poni from the Alexandru Ioan Cuza University of Iasi, who emphasised the importance of the salt springs from a number of areas of eastern Romania (viz. the Neam, Cacica and, respectively, Targu Ocna - Slanic Moldova depressions) starting with the Eneolithic Precucuteni and Cucuteni cultures [1-3]. More than 40 years ago, the Iasi archaeologist Nicolae Ursulescu published the first specialised study in Romania on the archaeological remains discovered in the proximity of salt springs, dating from the Neolithic (the Stareevo-Cris culture) to the Middle Ages [1, 4]. Following the discovery of a Chalcolithic tell at Poduri, then at Cucuieti and Tolici (the first in Bacau County, the second in Neam County), near salt springs, three groups of archaeologists started a series of researches on the possible relationship between these springs and the habitation in these tells [1, 5]. The problematics of salt spring exploitation was later tackled by a series of international research projects [1, 6-10]. The modern dating methods have allowed the confirmation of the archaeologists’ suppositions, and currently the oldest exploitation of salt from salt springs in Europe, perhaps in the world, dating from 6050-5500 B.C. (the Starcevo-Cris culture), is considered to be found at Lunca-Poiana Slatinei, Neamt County, Romania [1, 11]. The salt springs were also used by the later Chalcolithic communities [1, 12]. The paper presents the results obtained in the last years by our team concerning the obtaining, the chemical and physico-structural characterisation of saline aerosols, used in the prevention, therapy and production of environments with clean air. Analysis is performed on the first two sublevels from the first Aitken dispersion group of the trimodular systems (Aitken, medium and large/coarse or sedimentable). Thus, two subgroups can be distinguished in the first granulometric distribution of the Aitken particles, namely of hydrated particles, known as solions, and anhydrous particles, in the form of weakly superficially hydrated nanopolyhedrons. The solions have a mutable glomerular structure, which at the level of in vivo tissue through deliquescence allow directing the ions towards specific channels, activating biochemical processes, while the nanopolyhedrons, being strongly hydrophilic, will make chronic any affliction by strongly dehydrating the tissue. Two types of artificial solion-producing halochambers were experimented upon and patented by our team, which on account of their results were found to be originally effective in terms of the benefits for juvenile development (secondary school students), particularly for females, who * email: euroinvent@yahoo.com, chonceri@yahoo.fr; ion.sandu@uaic.ro