right ear dominance is one of the common findings across these DL syllable experiments. However, the assessment of contribution of every single stimulus to the final result would be of importance. This evaluation could also reveal the dynamic mechanisms behind the early and late cognitive processes. Such a task has been the basis of constructing an embedded interactive system (EMISU) in our laboratory. Accordingly, the system categorizes the on-line responses as well as the EEG traces into subgroups, allowing a post-analysis to study the dynamic and immediate changes throughout the recording session. Together with different stage analyses of electrophysiology and interac- tions, the information processing in the brain can be addressed. Furthermore, the application of DL in different states of pathology and states of consciousness can reveal some of the mechanisms behind the brain functioning under different conditions. doi:10.1016/j.ijpsycho.2008.05.504 EEG correlates of strategies used for making choice in uncertain conditions E.A. Levin a , O. Bayazit b , A. Oniz b , M. Ozgoren b a State Research Institute of Physiology, Laboratory of Memory Regulation Mechanisms, Novosibirsk, Russia b Dokuz Eylul University, Faculty of Medicine, Department of Biophysics, Izmir, Turkey Analytic approach to scientific experiment presumes that “all other conditions” must be kept “equal”. However, it could be not enough if such complex subjects as human beings, their behaviors, and neural activities underlying them are studied: it is necessary to take subjects' intrinsic complexity into account. Our study represents an example of such situation. Response patterns of subjects in dichotic tone listening paradigm were analyzed individually. This analysis revealed that some subjects' responses could not be accounted for involuntary “ear advantage” mechanism, proposed by dichotic listening paradigm, but could be rather explained by the use of response choice strategy. Induced and evoked EEG responses to stimuli presentations were measured to assess neural correlates of strategy-use in response selection. We observed two converging evidences of reciprocal interactions between frontal and parietal areas related to strategy use. (1) Latencies of ERP peaks (especially N2) in Strategy-users group (SU) were shorter than in Strategy-Non-Users (SNU) in frontal area, while in parietal area the relation was opposite. (2) Desynchronization in beta-band was stronger in SU than in SNU in frontal area, but in parietal area it was stronger in SNU than in SU. Also, (3) desynchronization in alpha-band was stronger in Strategy-users than in Strategy-non-users over right frontal and left temporoparietal areas. These findings could be considered as manifestations of top-down response selection control and its influence on bottom-up mechanisms. We propose that faster and stronger frontal activations in SU are associated with this control, while in SNU it is reduced leading to prevalence of bottom-up stimulus-driven processes associated with parietal activity. Pattern of alpha- desynchronizations could correspond to more active processes of encoding and/or verbalizing of stimuli in SU group. As a final remark, we should note that situation of forced choice in uncertain conditions is not uncommon in real life. It could be expected that propensity to use different strategies for solving such problems is a personality trait-like feature. Testing of this hypothesis opens a wide area for future research. Acknowledgement: This research was supported by TUBITAK-BIDEB 2216 — Research Fellowships for Foreign Country Citizens Program and by DEU Projects 2006.KB.SAG.17, 2005.KB.SAG. 069. doi:10.1016/j.ijpsycho.2008.05.505 SYMPOSIUM 33: Gene–Brain-Psychological Function Symposium Chair: O.V. Sysoeva (Russia); Co-Chair: A.P. Anokhin (USA) Psychophysiological aspects of birth stress and their genetic correlates I.M. Spivak a , T.Y. Smirnova a , N.A. Seilieva b , D.L. Spivak c a Institute of Cytology, Russian Academy of Sciences, Russia b Institute of Cytology, Russian Academy of Sciences, Russia; St. Petersburg State University, Saint-Petersburg, Russia c Human Brain Institute, Russian Academy of Sciences, St. Petersburg, Russia Complex processes taking place in the central nervous system, which condition active adaptation to unusual and extreme conditions, are at present regarded as being to certain extent genetically oriented. Such active adaptation implies the ability to involve hidden psychological reserves, to feel happiness or satisfaction, which may be in turn linked to religious feeling (Truett et al., 1992; Hamer, 1996; Holden, 1996; Lane et al., 1997). In our experiment attempt was taken to explore the possibility of correlation between psychophysiological aspects of birth stress, and genetic polymorph- isms of the renin–angiotensine system. These polymorphisms are presently linked to cardiovascular diseases, such as hypertension and left ventricular hypertrophy (Schneider et al., 2004). Birth stress was chosen for our research as being methodologically optimal, because it combines evolutionary expedience and genetic determination. Along with two-step psychological testing, and routine medical examination, determination of genetic poly- morphisms of genes of the rennin–angiotensine system (ACE and ANG) was conducted. ACE gene (angiotensine-converting enzyme) revealed insertion/ deletion polymorphism I/D), while ANG gene (angiotesinogene) revealed mononucleotide substitution М235T. After application of factor analysis, correlations between definite type of the ACE gene polymorphism and the level of neurotization were found. Disposition to neurotization in the unusual and/or extreme conditions could be in fact regarded as most plausibly inherited, and linked to carriage of the ‘weaker’, D-allele ACE gene. ANG polymorphism turned out to be gender-specific, and frequency of the ‘weak’ Т235 allele proved to be statistically significantly lower by women giving birth, compared to its level by the population in general. It was also shown that presence of the ‘strong’ М335 allele tends to positively correlate with such important aspect of psychological functioning as creativity. Finally, the ACE and ANG genes proved to belong to different groups detected by factor analysis. As a result, human genotype was proved to be linked to various aspects of the psychological functioning in humans, directed both towards negative (neurotization), and positive (creativity) consequences. This study was supported by grant 06-06-80048 issued by the Russian Foundation for Basic Research. References Hamer, D.H., 1996. The heritability of happiness. Nature Genetics 14, 125–126. Holden, C., 1996. Happiness and DNA. Science 272, 1591–1593. Lane, R.D., Reiman, E.M., Abern, G.L., Schwartz, G.E., Davidson, R.J., 1997. Neuroanato- mical correlates of happiness, sadness and disgust. American Journal of Psychiatry 154, 926–933. Truett, K.R., Eaves, L.J., Meyer, J.M., Heath, A.C., Martin, N.G., 1992. Religion and education as mediators of attitudes: a multivariate analysis. Behavior Genetics 22, 43–62. doi:10.1016/j.ijpsycho.2008.05.506 Inter-individual differences in time perception: Gene–brain- psychological function O.V. Sysoeva a , G.V. Portnova a , N.V. Maluchenko b , A.G. Tonevitsky b , A.M. Ivanitsky a a Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Russia b Moscow State University, Biological Faculty, Moscow, Russia The aim of our study was to investigate genetic determination of inter- individual differences in time perception and their relation to brain electrical activity. There is a substantial evidence for inter-individual differences in time perception (Tsykanov, 1996, Eisler, 2003). These differences may be genetically determined, whereby the path of action is probably mediated by some transmitter-specific subsystem. A relation between brain electrical oscillations (EEG) and internal time representation is often suggested (Treisman et al., 1994; Fonsova et al., 1997). Some components of event-related potential (ERP) is found to be related with stimulus duration (Sysoeva et al., 2006, 2007). Consequently, individual EEG characteristics should be also studied as putative neurophysio- logical correlates of individual time perception. In our study the association between the subjective time perception in different time regions and polymorphism of some genes, regulating the activity of serotonin (5-HT) and dopamine (DA), was examined. The brain activity (electroencephalogram, EEG) was registered during resting condi- tions (eyes open and eyes close), during production of subjective minute, and 189 Symposium abstracts / International Journal of Psychophysiology 69 (2008) 139–205