S1 Supporting information for Surrogate-based correlation models in view of real-time control of ozonation of secondary treated municipal wastewater - model development and dynamic validation Michael Chys 1,* , Wim T.M. Audenaert 1,‡ , Emma Deniere 1,2 , Séverine Thérèse F.C. Mortier 3,4 , Herman Van Langenhove 2 , Ingmar Nopens 3 , Kristof Demeestere 2,† , Stijn W.H. Van Hulle 1,† 1 LIWET, Department of Industrial Biological Sciences, Ghent University Campus Kortrijk, Graaf Karel de Goedelaan 5, B-8500 Kortrijk, Belgium 2 EnVOC, Department of Sustainable Organic Chemistry and Technology, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium 3 BIOMATH, Department of Mathematical Modelling, Statistics and Bioinformatics, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium 4 Department of Pharmaceutical Analysis, Ghent University, Ottergemsesteenweg 460, B-9000 Ghent, Belgium ‡ present affiliation: AM-TEAM, Advanced Modelling for Process Optimisation, Hulstbaan 63, B- 9112 Sint-Niklaas, Belgium * Corresponding author: Michael Chys, Phone: 00 32 56 24 12 06, Fax: 00 32 56 24 12 24, email: Michael.Chys@UGent.be; Michael.Chys@gmail.com † These authors contributed equally to the work. This SI includes 40 pages which contain 6 text sections, 10 tables and 21 figures related to TrOC analyses (SI-Text 1), (statistical) background on the model validity ( SI-Text 2, SI-Text 5 and SI-Text 6), determination of IOD (SI-Text 3) and HO• exposure (SI-Text 4), specific information on the abatement profiles of TrOCs in relation to UVA254 and fluorescence measurements, and statistical evidence supporting statements on the model validity.