B9 Health-related quality of life of adolescents with cerebral palsy in rural Bangladesh R POWER 1 , M MUHIT 2 , E HEANOY 3 , T KARIM 4 ,N BADAWI 5 , R AKHTER 6 , G KHANDAKER 7 1 Discipline of Child and Adolescent Health, Sydney Medical School, University of Sydney, NSW, Australia; Asian Institute of Disability and Development AIDD, University of South Asia, Dhaka, Bangladesh; 2 Asian Institute of Disability and Development AIDD, University of South Asia, Dhaka, Bangladesh; CSF Global, Dhaka, Bangladesh; 3 Asian Institute of Disability and Development AIDD, University of South Asia, Dhaka, Bangladesh; 4 Asian Institute of Disability and Development AIDD, University of South Asia, Dhaka, Bangladesh; CSF Global, Dhaka, Bangladesh; 5 Cerebral Palsy Alliance, The University of Sydney, Children’s Hospital at Westmead; 6 Faculty of Dentistry, the University of Sydney, NSW, Australia; 7 Asian Institute of Disability and Development AIDD, University of South Asia, Dhaka, Bangladesh; CSF Global, Dhaka, Bangladesh; Central Queensland Public Health Unit, Central Queensland Hospital and Health Service, Rockhampton, QLD, Australia Background and Objective(s): Health-related quality of life (HRQoL) is a subjective multidimensional concept for mea- suring the interaction between health status and physical, psy- chological, and social aspects of wellbeing. HRQoL is an important outcome measure for adolescents with cerebral palsy (CP) although there is a dearth of research in low and middle income countries (LMICs). The purpose of this study was to assess the health-related quality of life (HRQoL) of adolescents with cerebral palsy (CP) in rural Bangladesh. Study Design: Case-control study. Study Participants & Setting: 154 adolescents with CP (10 to ≤18 years, mean age 15y 1mo SD1y 8mo, female n=48) and 173 controls without disability (14y 11mo SD1y 7mo, female n=55) matched on age and sex participated in this study. This study was conducted in the Shahjadpur sub-district in the northern part of Bangladesh. Participants were identified through the Bangladesh Cerebral Palsy Register. Participation rate 80.2%. Materials/Methods: HRQoL was measured with Bengali ver- sions Cerebral Palsy Quality of Life-Teens (CPQoL-Teens), Kidscreen-27 and Strengths and Difficulties Questionnaire (SDQ). Questionnaires were interviewer administered to ado- lescents; primary caregivers were included for proxy-report. Concordance between self and proxy-report was assessed with intraclass correlation. Bivariate analysis and hierarchical multi- variable regression related HRQoL outcomes to sociodemo- graphic characteristics. Results: Adolescents with CP had poor to moderate HRQoL (CPQoL-Teens 38.5 SD27.4 to 71.5 SD16.1; Kidscreen-27 25.9 SD12.2 to 48.7 SD10.6). CPQoL-Teens ‘feelings about functioning’ and Kidscreen-27 ‘peers and social’ were poorest dimensions overall. High proportions of adolescents with CP had emotional, conduct, hyperactivity and/or peer problems (23.4% to 83.1%), a lot of pain (56.5%), felt sad (68.2%), lonely (71.4%) and concerned about the future (72.1%). Well- being was disproportionately poorer than controls (mean dif- ference Kidscreen-27 4.3 (95% CI 0.7 to 7.8) to 16.7 (95% CI 14.5 to 18.8) lower for cases, SDQ odds ‘probable’ mental health problems 1.6 (95% CI 0.4 to 5.6) to 13.3 (95% CI 6.3 to 28.0), p<0.050). Caregiver-proxies agreed with some but not all self-reports (n=64, ICC 0.5 to 09) and estimated poorer wellbeing (mean difference 2.2 (95% CI 0.7 to 3.7) to 7.7 (95% CI 4.2 to 11.3), p<0.050). Sociodemographic charac- teristics correlated to HRQoL; most notably non-school attendance and intellectual disability correlated to poorer HRQoL (r=0.180 to 0.383, p<0.050). Adolescent education was a predictor of three dimensions of HRQoL (7.7, 95% CI 0.4 to 15.0) to 10.3 (1.5 to 19.0), p<0.050). Conclusions/Significance: Adolescents with CP in rural Bangla- desh are at high risk of poor HRQoL including mental health problems. Effort to reduce inequality should target physical, psychological and social wellbeing with aim to improve long- term HRQoL of adolescents with CP in this region. B10 Depression, anxiety and stress among caregivers of adolescents with cerebral palsy in rural Bangladesh R POWER 1 , M MUHIT 2 , E HEANOY 3 , T KARIM 4 ,N BADAWI 5 , R AKHTER 6 , G KHANDAKER 7 1 Discipline of Child and Adolescent Health, Sydney Medical School, University of Sydney, NSW, Australia; Asian Institute of Disability and Development AIDD, University of South Asia, Dhaka, Bangladesh; 2 Asian Institute of Disability and Development AIDD, University of South Asia, Dhaka, Bangladesh; CSF Global, Dhaka, Bangladesh; 3 Asian Institute of Disability and Development AIDD, University of South Asia, Dhaka, Bangladesh; 4 Asian Institute of Disability and Development AIDD, University of South Asia, Dhaka, Bangladesh; CSF Global, Dhaka, Bangladesh; 5 Cerebral Palsy Alliance, The University of Sydney, Children’s Hospital at Westmead; 6 Faculty of Dentistry, the University of Sydney, NSW, Australia; 7 Asian Institute of Disability and Development AIDD, University of South Asia, Dhaka, Bangladesh; CSF Global, Dhaka, Bangladesh; Central Queensland Public Health Unit, Central Queensland Hospital and Health Service, Rockhampton, QLD, Australia Background and Objective(s): Caregivers of adolescents with cerebral palsy (CP) commonly report symptoms of depression, anxiety and stress, although little is known about wellbeing in low resource settings whereby disability is viewed as non-nor- mative and impairments are exacerbated by poverty. The pur- pose of this study was to determine the incidence, severity and predictors of depression, anxiety and stress among caregivers of adolescents with CP in rural Bangladesh to inform resource allocation and service design and implementation. Study Design: Case-control study. Study Participants & Setting: 154 caregivers of adolescents with CP (i.e. parent, grandparent, other relative or close adult friend who provided the majority of care and support to the adolescent) were matched by child age (10 to 18y) and sex to 173 caregivers of adolescents without disability. Partici- pants were identified through the Bangladesh Cerebral Palsy Register; participation rate 80.2%. Study was conducted in the Shahjadpur sub-district in the northern part of Bangla- desh. Materials/Methods: Symptoms of depression, anxiety and stress were assessed using the Bengali DASS-21 questionnaire. Bivari- ate analysis and hierarchical multivariable regression related DASS-21 outcomes to sociodemographic characteristics. Results: Majority of caregivers of adolescents with CP reported symptoms of depression (76.6%), anxiety (75.3%) and stress 14 Abstracts