INTERNATIONAL ARCHIVES OF MEDICINE SECTION: NURSING ISSN: 1755-7682 1 2020 Vol. 13 No. 7 doi: 10.3823/2623 © Creative Commons Attribution 4.0 International (CC BY 4.0) License International Medical Publisher http://imedicalpublisher.com Abstract Objectives: To assess an in situ simulation-based cardiopulmonary resuscitation training strategy, with emphasis on debriefng and fo- llow-up assessment of knowledge after training. Method: This was an educational intervention study to measure intraparticipant variability. The simulation-based teaching techniques consisted of nine steps.This research followed STROBE recommenda- tions for the methodological development of observational studies, "See Supplementary File 1". Results: Signifcant differences (p < 0.05) were observed between the pre-test and post-theory assessments, and between the pre- practical phase and 60 days post-training. However, no differences were observed (p<0.05) between the post-theory and post-practical phases, showing that after participating in the training strategy, after the pre-test assessment, the participants seemed to have carried over the knowledge displayed in the post-theory to the post-practical time, with considerable reduction in performance 60 days after the training program. Conclusion: Theoretical emphasis coupled with simulation practice displayed the best results in performance when compared to theore- tical training alone, even at 60 days post-training. Training for Nurses Using Realistic Simulation ORIGINAL Isabela Cristina de Oliveira 1 , Ledjane Neves de Oliveira 1 , Jeanne Liliane Marlene Michel 1 , Sueli Fátima Sampaio 1 , Ana Lucia Gargione Galvão de Sant’Anna 2 , Michelle Mayumi Yoshimura de Campos 2 , Regimar Carla Machado 2 1 Department of Nursing. Federal University of São Carlos, São Paulo, Brazil. 2 Paulista School of Nursing. Federal University of São Paulo, São Paulo, Brazil. Contact information: Regimar Carla Machado. Address: Paulista School of Nursing. Federal University of São Paulo. Napoleão de Barros Street, 754. Vila Clementino, Sao Paulo, Brazil.  regimarmachado@gmail.com Keywords Simulation; Nurses; Cardiopulmonary Resuscitation.