_____________________________________________________________________________________________________ *Corresponding author: E-mail: talhabmb@gmail.com; talha-bgctub@bgctrustbd.org; Journal of Advances in Microbiology 19(1): 1-10, 2019; Article no.JAMB.52114 ISSN: 2456-7116 Isolation of Pathogenic and Non-pathogenic Microbial Stains from Different Types of Sea Fish Samples and their Quality Assessment with Antibiogram Properties Asif Shahriar 1 , Taheera Akter 1 , Anina Tul Kobra 1 , Talha Bin Emran 2* , Jewel Mallick 2 and Mycal Dutta 2 1 Department of Microbiology, Stamford University Bangladesh, 51 Siddeswari Road, Dhaka-1217, Bangladesh. 2 Department of Pharmacy, BGC Trust University Bangladesh, Chandanaish, Chattogram-4381, Bangladesh. Authors’ contributions This work was carried out in collaboration among all authors. Authors AS, TA, ATK, TBE, JM and MD together planned and designed the research. Authors AS, ATK and TBE arranged the whole facilities for the research. Authors AS, TA and ATK conducted the entire laboratory works. Author AS imparted in study design and interpreted the results putting efforts on statistical analysis with authors JM, MD and TBE. All authors read and approved the final manuscript. Article Information DOI: 10.9734/JAMB/2019/v19i130185 Editor(s): (1). Dr. C. Ike, Anthony, Senior Lecturer, Department of Microbiology, University of Nigeria, Nsukka, Enugu State, Nigeria. Reviewers: (1). Forcep Rio Indaryanto, University of Sultan Ageng Tirtayasa, Indonesia. (2). Ir. F. Feliatra, University of Riau, Indonesia. Complete Peer review History: http://www.sdiarticle4.com/review-history/52114 Received 17 August 2019 Accepted 22 October 2019 Published 22 November 2019 ABSTRACT Aims: The contamination of sea fish and seafood by bacteria of fecal origin along with various pathogenic drug-resistant microorganisms are widely documented as the cause of several human diseases. Our present studies aim to determine the comparative microbiological quality among raw, cooked and cooked-frozen fish along with antimicrobial profiling of those isolated pathogenic and non-pathogenic microbes with potential drug modelling and increasing the awareness of taking unnecessary antibiotics. The objective of the present study was to investigate the status of fish in cold condition after cooking. Original Research Article