Research Article Effects of Second-Order Slip Flow and Variable Viscosity on Natural Convection Flow of (CNTs - Fe 3 O 4 )/Water Hybrid Nanofluids due to Stretching Surface Ayele Tulu and Wubshet Ibrahim Department of Mathematics, Ambo University, Ambo, Ethiopia Correspondence should be addressed to Ayele Tulu; ayeletulu@ymail.com Received 7 August 2020; Revised 25 October 2020; Accepted 9 March 2021; Published 19 March 2021 Academic Editor: Mostafa S. Shadloo Copyright © 2021 Ayele Tulu and Wubshet Ibrahim. is is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. is study deals with natural convection unsteady flow of CNTs Fe 3 O 4 /water hybrid nanofluids due to stretching surface embedded in a porous medium. Both hybrid nanoparticles of SWCNTs Fe 3 O 4 and MWCNTs Fe 3 O 4 are used with water as base fluid. Effects of hybrid nanoparticles volume friction, second-order velocity slip condition, and temperature-dependent viscosity are investigated. e governing problem of flow is solved numerically employing spectral quasilinearization method (SQLM). e results are presented and discussed via embedded parameters using graphs and tables. e results disclose that the thermal conductivity of (CNTs Fe 3 O 4 )/H 2 O hybrid nanofluids is higher than that of CNTs H 2 O nanofluids with higher value of hybrid nanoparticle volume fraction. Also, the results show that momentum boundary layer reduces while the thermal boundary layer gros with higher values of temperature-dependent viscosity and second-order velocity slip parameters. e skin friction coefficient improves, and the local heat transfer rate decreases with higher values of nanoparticle volume fraction, temperature-dependent viscosity, and second-order velocity slip parameters. Furthermore, more skin friction coefficients and lower local heat transfer rate are reported in the CNTs Fe 3 O 4 /H 2 O hybrid nanofluid than in the CNTs H 2 O nanofluid. us, the obtained results are promising for the application of hybrid nanofluids in the nanotechnology and biomedicine sectors. 1. Introduction e broad applications of heat transfer in various sectors of industry and biomedicine have required the accessibility of efficient thermal performance techniques. In the past few decades, several techniques of enhancing the thermal per- formance of working fluids have been realized by different researchers. Scattering of nanoparticles of metallic structures such as copper, carbides, alumina, nitrides, metal oxides, carbon nanotubes, and graphite in the working fluid is considered to be one of the innovative and efficient methods (Mahanthesh et al. [1]). At present, nanofluids are the noble options for the heat transfer fluids due to their remarkably higher thermal conductivity, and their use is common in heat exchangers, cooling systems, solar energy, biomedicine, and so forth (Aziz et al. [2]). Besides, the porous media have better dissipation area, which results in improved convective heat transfer. As a result, Reddy and Sreedevi [3] analyzed heat and mass transfer characteristics of nanofluid flow over porous stretching sheet. e non-Newtonian Casson nanofluid flow and heat transfer over stretching cylinder in a porous medium were investigated by Tulu and Ibrahim [4]. Furthermore, the effect of temperature and concentration on the thermal conductivity of ZnO-TiO/EG hybrid nanofluid using artificial neural network and curve fitting on exper- imental data was evaluated by Safaei et al. [5]. At present, heat transfer of carbon nanofluids (CNTs) has received great attention due to their potential applica- tions in the fields of nanotechnology and biomedicine. CNTs are allotropes of carbon prepared in cylindrical tubes of graphite with nanometer in diameter and a few millimeters in length (Hirlekar et al. [6]). CNTs are generally divided into single-wall carbon nanotubes (SWCNTs) and multiwall carbon nanotubes (MWCNTs) depending on their number Hindawi Mathematical Problems in Engineering Volume 2021, Article ID 8407194, 18 pages https://doi.org/10.1155/2021/8407194