Send Orders for Reprints to reprints@benthamscience.ae Current Medical Imaging Reviews, 2015, 11, 3-14 3 A Survey on Medical Image Segmentation Saleha Masood*, Muhammad Sharif, Afifa Masood, Mussarat Yasmin and Mudassar Raza Department of Computer Science, COMSATS Institute of Information Technology, Wah Cantt, Pakistan Abstract: Much work has been done in the field of Image segmentation but still there is a room for improvement. Medical image segmentation is a sub field of image segmentation in digital image proc- essing that has many important applications in the prospect of medical image analysis and diagnostics. Here in this paper different approaches of medical image segmentation will be classified along with their sub fields and sub methods. Recent techniques proposed in each category will also be discussed followed by a comparison of these methods. Keywords: Atlas guided methods, Bayesian method, classifiers, clustering, deformable models, Markov random field, Medical image segmentation, modalities, neural networks, region growing, thresholding. 1. INTRODUCTION Segmentation is a process in which an image is divided into several sub regions based on a specific feature in order to pick up a region of interest. Segmentation process has enormous applications in the medical field. In the field of research and development much work has been done to overcome the problems faced by the segmentation process and yet there is a need of more effective and efficient work. 1.1. Purpose of Medical Image Segmentation In the process of segmentation of a medical image, the details required by the segmentation process are highly de- pendent on clinical application of the problem [1]. The pur- pose of segmentation is to improve the process of visualiza- tion to handle the detection process more effectively and efficiently. Other reasons of medical image segmentation can be seen in Fig. (1). Fig. (1). Purpose of segmentation. *Address correspondence to this author at the Department of Computer Science, COMSATS Institute of Information Technology, Wah Cantt, Pakistan; E-mail: salehamasood08@gmail.com The analysis of functions of anatomy problems is carried out through the segmentation process [2]. It covers all the factors that influence the analysis of a disease. Through the process of segmentation one can analyze, diagnose, quantify, monitor and plan the navigation of a disease. 1.2. Basic Principles of Segmentation The process of segmentation is carried out on the basis of two central principles. These principles as shown in Fig. (2) are classified on the basis of features that contain texture, intensity, sharpness of edges and all the significant features in this context [3]. Fig. (2). Basic principles of segmentation. 1.3. Problems in Medical Image Segmentation Segmentation of medical image faces many problems be- cause of which the quality of segmentation process gets af- fected [4]. These problems can be analyzed in Fig. (3) below. The problem of uncertainty arises when there is noise in the image which makes the classification of image difficult [5]. The reason is that intensity values of pixels are amended because of noise in the image. This alteration in the intensity values of pixels disturbs uniformity in the intensity range of                           1875-6603/15 $58.00+.00 ©2015 Bentham Science Publishers