MO881 LUNG ULTRASONOGRAPHY AND BIOIMPEDANCE IN ASSESSMENT OF VOLUME STATUS OF HEMODIALYSIS PATIENTS: A COMPARISON BETWEEN BOTH METHODS C atia Figueiredo 1 , Marisa Rold~ ao 1 , Ana Rita Valerio Alves 1 , Hern^ ani Gonc ¸alves 1 , Flora Sofia 1 , Karina Lopes 1 1 Rainha Santa Isabel Hospital - Centro Hospitalar Me ´dio Tejo, EPE, Nephrology, Torres Novas, Portugal BACKGROUND AND AIMS: Assessment of volume status is an important prognostic factor in hemodialysis (HD) patients. Several methods have been suggested to estimate it: bioimpedance analysis, brain natriuretic peptide levels (BNP) and lung and inferior vena cava (IVC) ultrasonography (US), which are emerging as a valuable technique in this field. Our aim was to evaluate effectiveness of lung US in assessment of volume status in chronic HD patients and compare it with the gold standard bioimpedance technique. METHOD: Cross-sectional study of 58 prevalent HD patients. Several analytical data were analyzed, including BNP, albumin and sodium levels. Lung and IVC US were performed to assess the presence and distribution of B-lines and the diameter and respiratory collapsibility of IVC, respectively. FreseniusV R body composition monitor (BCM) was the bioimpedance technique used. It defines hyperhydration as relative fluid overload (RFO) >15%. Both US and BCM were performed at the same day, immediately before the middle week HD session. Categorical variables are presented as frequencies and percentages, continuous variables as means and standard deviations, or medians and interquartile ranges (IQR) for variables with skewed distributions. Statistical analysis was performed using SPSSV R version 25 for Windows. RESULTS: The average age was 75.361.6 years and 56.9% were male. The average time in HD was 36.664.1 months. Half of the patients (n=29) presented B-lines in lung US. The diameter of IVC was significantly higher in this group of patients, both inhaling (1.360.4 vs 0.960.4; p=0.001) and exhaling (2.060.4 vs 1.660.5; p<0.001). Similarly, most patients with B-lines at lung US presented collapsibility of IVC < 50% (n=25; 89.3%). Although not statistically significant, the RFO was higher in patients with presence of B-lines compared to those who did not present it (10.2610.6% vs 5.466.9%; p=0.061). Considering the mean RFO value in patients with B-lines, we observed that its presence was significantly higher in patients with RFO > 10% compared to those with RFO < 10% (58.6% vs 31%; p=0.035). Besides, patients with RFO > 10% also presented higher BNP (9878634646 pg/mL vs 394568634 pg/mL; p=0.009) and lower albumin levels (3.460.5 vs 3.760.4; p= 0.039) than other group. CONCLUSION: Lung US seems to be a valuable tool to diagnose overhydration earlier than BCM, which currently defines hyperhydration as RFO >15%. In this study we verified that patients with lower levels of RFO (>10%) already presented signals of fluid overload, such as presence of B-lines at lung US, higher BNP and lower albumin levels. These findings support the benefit of lung US in guiding fluid removal and may change the practice in our HD unit to probe the ideal dry weight for chronic dialysis patients. MO882 PATIENTS’ UNDERSTANDING AND EXPERIENCE OF COVID- 19 PANDEMIC AMONGST IN-CENTRE HAEMODIALYSIS POPULATION IN A SINGLE UK CENTRE Khai Ping Ng 1 , Lisa Crowley 1 , Yogita Aggarwal 1 , Jyoti Baharani 1 1 University Hospitals Birmingham NHS Foundation Trust, Renal medicine (Heartlands), Birmingham, United Kingdom BACKGROUND AND AIMS: Patients with end-stage kidney disease on dialysis are susceptible to severe COVID-19 infections. However, during the pandemic, many renal patients were unable to ‘shield’ fully due to the ongoing need to attend the dialysis unit for treatment. With a significant proportion of our haemodialysis population coming from socially deprived and ethnic minority background (38%), we aimed to explore patients’ understanding and experience of COVID-19 pandemic. METHOD: This was a cross-sectional survey of patients receiving in-centre haemodialysis from one centre in England conducted during July 2020, three months after the first UK national lockdown. The questionnaire consisted of 18 questions exploring patients’ awareness of COVID-19 pandemic, understanding of ‘shielding’, use of face covering, and their experience of haemodialysis treatment as well as accessing healthcare during COVID-19 pandemic. Those with language barriers were offered assistance and verbal translation by haemodialysis nurses, if possible, to complete the questionnaire. RESULTS: In total, 232 patients (of a total of 479 in-centre dialysis patients, 48% response rate) completed and returned the questionnaire. Of these, 29 (12.5%) patients required help with the questionnaire due to language barrier. Mean age was 62 (SD 16) years, 63% were male, 53% were from ethnic minorities and 45% were from the most deprived area (MDI Decile 1). A third of the respondents lived with 3 or more adults at home and a quarter lived with one or more child. Majority of the patients (97%) were aware of COVID-19 pandemic, and most received information on COVID-19 from the news (87%). Dialysis staff (43.1%), family and friends (32.6%), internet (31%) and general practitioners (20.3%) were also key sources of information. Despite this, 17.2% of the patients did not know about ‘shielding’. Even though 3 in 4 patients stated that they were ‘always’ or ‘often’ able to ‘shield’, when prompted with scenarios, significant number of patients in fact felt that they were unable to shield when travelling to dialysis (56%), during dialysis (35%) or when shopping (17%). Majority of the patients (89%) said that they wore face covering and 28% self-isolated from the rest of household during the first peak of pandemic. 83% practised ‘social distancing’ at dialysis units but 5% did not and 6% felt unable to do so. Almost a quarter of the patients (23%, 54 patients) felt unwell during the first wave of COVID-19. Majority (50%) of them sought medical help by informing the dialysis unit, whilst 26% contacted their GP and 38% attended emergency departments. Of these 54 patients, 35% had difficulties accessing medical help, especially from primary care. One in four patients felt that their dialysis experience had changed during the pandemic: 10% increased use of private taxis or used different travel services, 3.5% reported increased travel time, 8% dialysed at a different unit, 5% experienced longer waiting time to start dialysis sessions and 4% had dialysis frequency reduced . Almost a third (29%) of the patients knew of someone in the dialysis unit who had COVID-19 infection during the first wave of pandemic. CONCLUSION: COVID-19 posed significant challenges for patients receiving in- centre haemodialysis. Despite their high susceptibility to severe COVID infection, significant number of patients was not aware of ‘shielding’ or able to ‘shield’ effectively. Some also experienced difficulties accessing medical help and a quarter reported change of transport or dialysis arrangement during the pandemic. MO883 FATIGUE IS THE PREDOMINANT PATIENT-REPORTED OUTCOME MEASURE IN HEMODIALYSIS PATIENTS: RESULTS OF A MULTICENTER CROSS-SECTIONAL EPROMS STUDY Abdallah Guerraoui 1 , Anne Kolko-Labadens 2 , Mathilde Prezelin-Reydit 3 , Philippe Chauveau 3 , Catherine Lasseur 3 , Marie Lino-Daniel 1 , Julie Haesebaert 4 , Agnes Cailette-beaudoin 1 1 Calydial, Nephrology-Dialysis, Vienne, France, 2 AURA Paris, Nephrology-Dialysis, Paris, France, 3 Aurad-aquitaine, Nephrology-Dialysis, Gradignan, France and 4 Universitaire Lyon, HESPER, Lyon, France BACKGROUND AND AIMS: End Stage renal disease (ESRD) and hemodialysis are associated with a decrease in quality of life (QOL). Self-reported QOL symptoms are not always prioritized by the medical team, potentially leading to conflicting priorities with patients. Electronic patient-reported outcome measures (ePROMs) allow physicians to better describe these symptoms. The objective was to describe the prevalence of symptoms self-reported by HD patients. METHOD: A multicenter cross-sectional study was conducted in three HD centers. Patients were included if they were 18 years old or over and treated with HD for at least three months in a center. Data were collected by the patient via a self-administered ePROMs questionnaire. Data included patient characteristics, post-dialysis fatigue and intensity, recovery time after a session, perceived stress, impaired sleep the day before the dialysis session, current state of health, and the one-year change. RESULTS: In total, we included 173 patients with a mean age of 66.2 years, a mean 6 Nephrology Dialysis Transplantation Abstracts 10.1093/ndt/gfab100 | i487 Downloaded from https://academic.oup.com/ndt/article/36/Supplement_1/gfab100.008/6289393 by guest on 25 November 2021