Accepted Manuscript Title: Detection and quantication of the selective EP4 receptor antagonist CJ-023423 (grapiprant) in canine plasma by HPLC with spectrouorimetric detection Author: Virgina De Vito Alessandro Saba Hong-Ki Lee Helen Owen Amnart Poapolathep Mario Giorgi PII: S0731-7085(15)30224-7 DOI: http://dx.doi.org/doi:10.1016/j.jpba.2015.11.004 Reference: PBA 10327 To appear in: Journal of Pharmaceutical and Biomedical Analysis Received date: 26-5-2015 Revised date: 2-11-2015 Accepted date: 3-11-2015 Please cite this article as: Virgina De Vito, Alessandro Saba, Hong-Ki Lee, Helen Owen, Amnart Poapolathep, Mario Giorgi, Detection and quantication of the selective EP4 receptor antagonist CJ-023423 (grapiprant) in canine plasma by HPLC with spectrouorimetric detection, Journal of Pharmaceutical and Biomedical Analysis http://dx.doi.org/10.1016/j.jpba.2015.11.004 This is a PDF le of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its nal form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.