_____________________________________________________________________________________________________ *Corresponding author: E-mail: charlesfokunang@yahoo.co.uk; Journal of Advances in Medical and Pharmaceutical Sciences 20(4): 1-15, 2019; Article no.JAMPS.49004 ISSN: 2394-1111 Evaluation of the Therapeutic Approach and Outcome of Type 2 Diabetes Mellitus Management Strategies in Cameroon Lukong Marie Chantal Suinyuy 1 , Tembe Estella Fokunang 1 , Dehayen Mesmin 2 , Ngo Valery Ngo 3 and Charles Ntungwen Fokunang 1* 1 Department of Pharmacotoxicology and Pharmacokinetics, University of Yaoundé, Cameroon. 2 Department of Internal Medicine and Specialties, University of Yaoundé 1, Cameroon. 3 Department of Global Health, Sahlgrenska Institute of Medicine, The University of Gothenburg, Sweden. Authors’ contributions This work was carried out in collaboration among all authors. Authors CNF, LMCS and TEF designed the study, performed the statistical analysis, wrote the protocol, and wrote the first draft of the manuscript. Author NVN and Author DM managed the analyses of the study. Author TEF managed the literature searches. All authors read and approved the final manuscript. Article Information DOI: 10.9734/JAMPS/2019/v20i430115 Editor(s): (1) Dr. Hamdy A. Sliem, Professor, Internal Medicine, Suez Canal University, Egypt and, College of Dentistry, Qassim University and EL-Jouf University, Saudi Arabia. Reviewers: (1) E. Siva Rami Reddy, Tantia University, India. (2) Rupali Sengupta, SNDT Women's University, India. Complete Peer review History: http://www.sdiarticle3.com/review-history/49004 Received 27 February 2019 Accepted 11 May 2019 Published 30 May 2019 ABSTRACT Introduction: Type 2 diabetes mellitus (T2DM) is a metabolic syndrome that is characterized by chronic hyperglycaemia, and can lead to chronic long-term complications. The prevalence of diabetes mellitus in Cameroon has been reported at 5.9% in 2017. Studies conducted in 2011, showed that only 41% of patients had a good glycaemic control which was, HbA1c < 6.5. The aim of this study was therefore to evaluate the treatment intensification with time in T2DM patients in the Yaoundé diabetic Centre in Cameroon. Methods: The study was a cross-sectional analytical study. In a group of T2DM patients followed up at the National Obesity Centre (NOC) with poorly controlled blood sugar (HbA1c ≥ 7%). The treatment intensification and outcome were evaluated between the periods January 2016 to April Original Research Article